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OpenTrials
Completed

NCT Number: NCT02522039

Pupillary Response After Glaucoma Medication

Investigation of the effect on the pupillary constriction by latanoprost, dorzolamide,timolol in healthy subjects. The pupillary constriction is compared to no drug.

Completed

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Key information

Conditions

Drug Effect (Glaucoma Drugs)

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Glostrup University Hospital

Glostrup Municipality, DK-2600, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects

Exclusion criteria

  • ophthalmological diseases
  • systemic disease
  • smoking
  • refractive error >= 6 diopters

Treatment and study plan

latanoprost

Drug

1 drop of latanoprost was given to study eye after washout period of 1 week between drugs

Timolol

Drug

1 drop of timolol was given to study eye after washout period of 1 week between drugs

Other names: Optimol

Dorzolamide

Drug

1 drop of dorzolamide was given to study eye after washout period of 1 week between drugs

Primary outcomes

  1. pupillary constriction measured as the post-illimination pupillay response (PIPR)

    Time frame: 1 day

    The pupillary diameter 0 to 10 seconds after light stimulation, the diameter is measured relative to the initial dark adapted pupil diameter

Sponsors and collaborators

Lead sponsor

Glostrup University Hospital, Copenhagen

Other

Registry information

Official study title

Effect of Topical Anti-glaucoma Medications on Late Pupillary Light Reflex, as Evaluated by Pupillometry

Acronym: pupil

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Aug 13, 2015
Registry last updated
Aug 13, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.