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Completed

NCT Number: NCT05289414

Pulsed Radiofrquency Targeting Mid Cervical Medial Branches Versus GON for Cervicogenic Headache

To detect the Clinical efficacy of pulsed radiofrequency treatment targeting the mid cervical medial branches versus greater occipital nerve for cervicogenic headache

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Key information

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tarek

Asyut, Egypt

About this study

Cervicogenic headache (CHA) is one of the secondary headache disorders. The prevalence of CHA was estimated to be ~4.1%, and most of the patients affected by CHA report un-resolved, recurrent throbbing pain.

it has been treated with many treatment modalities, such as the administration of medi-cines, physiotherapy, transcutaneous electrical nerve stimulation, and interventional pro-cedures. However, these treatments do not result in long-term relief for many patients and need to be repeated Pulsed radiofrequency treatment (PRF) is one of the modalities used to treat CHA

. CHA has been known to originate from the convergence of the 3 upper cervical and tri-geminal afferents, and therefore, many physicians have performed PRF targeting the upper cervical structures (occipital nerve, C2 dorsal root ganglion).

However, this results in only short-term pain relief in the posterior head, and it can lead to some complications, such as vascular and nerve injuries. Because of these limitations, we will attempt PRF targeting the mid-cervical medial branches

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • medically stable outpatients with confirmed diagnosis of cervicogenic headache according to International Headache society
  • Are reliable and willing to make themselves available for the duration of the study and are willing to follow up.
  • Men or women older than 18years of age .
  • clear written informed consent from each participant in the trial.

Exclusion criteria

1)pregnants, breastfeeding, or willing to be pregnant during the study.

2)presence of clinically significant medical or psychiatric condition that may increase the risk associated with the study 3)participation in any other type of medical research that may interfere with the interpretation of the study.

4)patients with haemocoagulation disorders, local infection or those who refused to consent

Treatment and study plan

Radiofrequency on mid cervical medial branches

Device

patients with diagnosis of cervicogenic headache will be subjected to radiofrequency on mid cervical medial branches

Radiofrequency

Device

patients with diagnosis of cervicogenic headache will be subjected to radiofrequency on Greater occipital nerve

Primary outcomes

  1. visual analog scale (VAS)

    Time frame: 6 months

    Assessment of pain will be done using VAS The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."

Secondary outcomes

  1. Visual analogue scale

    Time frame: 3 months

  2. visual analogue scale

    Time frame: 1 month

  3. visual analogue scale

    Time frame: 2 weeks

  4. visual analogue scale

    Time frame: 48 hours

  5. patient satisfactory score

    Time frame: 6 month

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Clinical Efficacy of Pulsed Radiofrequency Treatment Targeting the Mid Cervical Medial Branches Versus Greater Occipital Nerve for Cervicogenic Headache

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Mar 21, 2022
Registry last updated
Mar 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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