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OpenTrials
Completed

NCT Number: NCT01529996

Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness

The primary objective of this study is to compare the efficacy of PDL and the 1064-nm Nd:YAG laser in the treatment of facial redness.

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Key information

Conditions

Rosacea Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, Illinois, 60611, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy patients 18-55 years of age with erythematotelangiectatic rosacea (as verified by the the PI).
  • Subjects who are willing to provide informed consent for participation in the study.

Exclusion criteria

  • Pregnant or lactating individuals
  • Subjects who are unable to understand the protocol or to give informed consent.
  • Subjects who have a known history of photosensitive conditions (e.g. Systemic lupus, polymorphous light eruption)
  • Subjects who have facial telangiectasia of diameter greater than 2 mm.
  • Subject who have significant (as determined by the PI) acute inflammatory papules, pustules, and vesicle involving the central face.

Treatment and study plan

Pulse Dye Laser/YAG laser

Procedure

This study involves treatments with two types of lasers, Pulsed dye lasers (PDL) and the 1064 nm Nd: YAG. Both lasers are FDA approved to treat vascularities in the skin.

Primary outcomes

  1. Rating on global improvement scale

    Time frame: four months

    Non-treating dermatologists will rate each side of the face using a global improvement scale to evaluate the effectiveness of the two treatments.

  2. Spectrophotometer measurement

    Time frame: four months

    Spectrophotometer measurement as the percent resolution on each follow up visit compared to baseline visit

Secondary outcomes

  1. Patient satisfaction

    Time frame: four months

    Patients will record satisfaction on the questionnaires provided

  2. Recorded discomfort

    Time frame: four months

    Subjects will record discomfort using a 10-point scale

  3. Adverse events

    Time frame: four months

    Any adverse events will be recorded

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Official study title

Comparison of the Efficacy Between Pulsed Dye Laser (PDL) and the Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness: A Pilot, Prospective Randomized Trial.

Important dates

Study start
2012
Primary completion
2012
Study completion
2012
First posted
Feb 9, 2012
Registry last updated
Dec 2, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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