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Completed

NCT Number: NCT03227341

Pulmonary Rehabilitation in Asthma Control

The investigators compared the effectiveness of pulmonary rehabilitation program on asthma control in patients with uncontrolled and partially controlled asthma.

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Key information

About this study

Asthma treatment is not only medical, it also requires a comprehensive care including nonpharmacological treatment. Pulmonary rehabilitation represents the most important part of the comprehensive care. The investigators aimed to evaluate the efficacy of pulmonary rehabilitation in patients with uncontrolled and partially controlled asthma.

Asthma patients referred to pulmonary rehabilitation (PR) unit were classified according to asthma control test; as partially controlled patients (Group 1), and as uncontrolled patients (Group 2). All patients received of a 8 week pulmonary rehabilitation program. Asthma control tests, pulmonary function tests, arterial blood gases analysis, dyspnea perception, quality of life, exercise capacity, anxiety and depression assessments were performed before and after pulmonary rehabilitation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Asthmatic patients referred from the outpatient clinic to Pulmonary Rehabilitation unit was confirmed according to GINA guidelines

Exclusion criteria

  • If the initial diagnosis cannot be confirmed, the patient excluded from the study
  • Patients were under medical treatment of -6 months and considered clinically stable.
  • Patients with cardiovascular, other lung diseases (pneumoconiosis, pulmonary tuberculosis, interstitial lung disease), or musculoskeletal diseases that would impair exercise training were excluded from the study.
  • Also subjects with lack of motivation, poor compliance (not attending the program more than 2 times) or having transport problems were excluded from the study

Treatment and study plan

Exercise

Other

8 week exercise program including breathing exercises consisted of pursed-lip breathing, diaphragmatic breathing and thoracic expansion exercises, relaxation and stretching exercises, upper and lower extremity muscle strength training, and aerobic exercises. In addition, bronchial hygiene techniques and dyspnea-reducing positions

Primary outcomes

  1. Asthma control test score

    Time frame: 4 weeks

    A test measured the control of asthma

Secondary outcomes

  1. Exercise capacity

    Time frame: 6 minute

    Six minute walk test

  2. Dyspnea

    Time frame: 1 year

    MMRC Dyspnea Scale

  3. Quality of Life

    Time frame: 1 year

    St. George Respiratory Questionnaire

  4. Pulmonary Function Test

    Time frame: 1 hour

    FEV1, FVC, DLCO

  5. Arterial Blood Gas

    Time frame: 1 hour

    PaO2, PaCO2, SaO2

  6. Anxiety and Depression

    Time frame: 1 week

    Hospital Anxiety and Depression Scale

Sponsors and collaborators

Lead sponsor

Izmir Katip Celebi University

Other

Registry information

Official study title

Does Pulmonary Rehabilitation Contribute to Asthma Control?

Important dates

Study start
2013
Primary completion
2017
Study completion
2017
First posted
Jul 24, 2017
Registry last updated
Jul 24, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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