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Completed

NCT Number: NCT06186713

Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function

Pulmonary hypertension (PH) has a negative effect on acute myocardial infarction (AMI) patients and appears to be closely associated with reduced left ventricular function. However, its impact on AMI patients with reduced left ventricular function remains unclear. This retrospective study included AMI patients with reduced left ventricular function to investigate the prognostic value of PH in this specific type of patient. Meanwhile, a nomogram would be established basing on the identified independent risk factors, hoping to provide a novel risk stratification for them.

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Key information

Conditions

Acute Myocardial Infarction Cardiovascular Diseases Hypertension Hypertension, Pulmonary Lung Diseases Pulmonary Hypertension Respiratory Tract Diseases Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

First Affiliated Hospital of Xian Jiaotong University

Xi'an, Shaanxi, 710061, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The patients who were hospitalized for AMI with reduced left ventricular function at the First Affiliated Hospital of Jiaotong University from January 2018 to January 2022.

Exclusion criteria

  • Myocardial infarction complicated by cardiac rupture.
  • Significant pre-existing heart failure.
  • Other comorbidities such as malignancy that may significantly affect prognosis.
  • Incomplete clinical data.

Treatment and study plan

This was an observational study, and no Intervention was given to the patients.

Other

This was an observational study, and no Intervention was given to the patients.

Primary outcomes

  1. The incidence of all-cause death

    Time frame: 1-year after the AMI.

    All-cause death will be determined by clinical records or phone calls with patients and their family.

Sponsors and collaborators

Lead sponsor

First Affiliated Hospital Xi'an Jiaotong University

Other

Registry information

Official study title

Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function (STIMULATE): A Single-center, Retrospective Cohort Study

Acronym: STIMULATE

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jan 2, 2024
Registry last updated
Jan 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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