Pulmonary Hypertension in Lymphangioleiomyomatosis

This is a descriptive study of patients with Lymphangioleiomyomatosis and precapillary pulmonary hypertension.

Completed

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Key information

Conditions

Lymphangioleiomyomatosis Cardiovascular Diseases Hemic and Lymphatic Diseases Hypertension Hypertension, Pulmonary Immune System Diseases Immunoproliferative Disorders Lung Diseases Lymphangiomyoma Lymphatic Diseases Lymphoproliferative Disorders Neoplasm, Lymphatic Tissue Neoplasms Neoplasms by Histologic Type Neoplasms, Connective and Soft Tissue Perivascular Epithelioid Cell Neoplasms Pulmonary Hypertension Respiratory Tract Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Louis Pradel Hospital

Lyon, University of Lyon, 69677, France

About this study

Descriptive study of patients with Lymphangioleiomyomatosis and precapillary pulmonary hypertension This will include modality of diagnosis of lLymphangioleiomyomatosis, results of right-sided heart catheterization, and pulmonary function tests

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Lymphangioleiomyomatosis (definite or probable), either sporadic or associated with tuberous sclerosis
Precapillary pulmonary hypertension, as defined by right-sided heart catheterization (mean pulmonary artery pressure higher than 25 mmHg, wedge capillary pulmonary pressure less than 15 mmHg, pulmonary vascular resistance higher than 3 Wood units)

Exclusion criteria

Post capillary pulmonary hypertension
Other identifiable causes of pulmonary hypertension (ex: thromboembolic disease)
Not willing to participate

Sponsors and collaborators

Lead sponsor

Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires

Other

Collaborators

Hospices Civils de Lyon

Registry information

Official study title

Observational Study of Patients With Lymphangioleiomyomatosis and Pulmonary Hypertension

Acronym: LAM-PH

Important dates

Study start: 2009
Primary completion: 2009
Study completion: 2010
First posted: Aug 18, 2009
Registry last updated: Oct 27, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed