NCT Number: NCT01208272
Psychological Treatment of Overweight Binge Eaters
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED.
Looking for future studies?
Notify MeKey information
Conditions
Age range
18 year–65 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Phase 1 / Phase 2
Primary location
Yale University, New Haaven, Connecticut, United States
About this study
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED. METHODS: One hundred sixty-two overweight patients meeting DSM-IV criteria for BED were randomly assigned to 20 weekly sessions of either group CBT or group IPT. Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at posttreatment, and at 4-month intervals up to 12 months following treatment. RESULTS: Binge-eating recovery rates were equivalent for CBT and IPT at posttreatment (64 [79%] of 81 vs 59 [73%] of 81) and at 1-year follow-up (48 [59%] of 81 vs 50 [62%] of 81). Binge eating increased slightly through follow-up but remained significantly below pretreatment levels. Across treatments, patients had similar significant reductions in associated eating disorders and psychiatric symptoms and maintenance of gains through follow-up. Dietary restraint decreased more quickly in CBT but IPT had equivalent levels by later follow-ups. Patients' relative weight decreased significantly but only slightly, with the greatest reduction among patients sustaining recovery from binge eating from posttreatment to 1-year follow-up. CONCLUSIONS: Group IPT is a viable alternative to group CBT for the treatment of overweight patients with BED. Although lacking a nonspecific control condition limits conclusions about treatment specificity, both treatments showed initial and long-term efficacy for the core and related symptoms of BED.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- DSM-IV research criteria for binge-eating disorder
- Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
- Marked stress regarding binge eating
- At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
- 18-65 years old
- Body mass index, 27-48 kg/m squared
Exclusion criteria
- Pregnant or planning to become pregnant
- Taking weight-affecting or psychotropic medications
- Psychiatric conditions warranting immediate treatment
- Current enrollment in psychotherapy or a weight loss program
Treatment and study plan
Interpersonal Therapy (IPT)
BehavioralPrimary outcomes
-
To investigate the short and long-term efficacy of two treatments for binge eating among the overweight: Group Cognitive-Behavior (CBT) and Group Interpersonal Therapy (IPT).
Assessments of binge eating and associated eating disorder paychopathology, general psychological functioning, and weight occurred before treatment, at post treatment, and at 4-month intervals up to 12 months following treatment.
Sponsors and collaborators
Lead sponsor
Washington University School of Medicine
Other
Registry information
Official study title
A Randomized Comparison of Group-Behavioral Therapy and Group Interpersonal Psychotherapy for the Treatment of Overweight Individuals With Binge-Eating Disorder
Important dates
- Study start
- 1994
- Primary completion
- 1998
- Study completion
- 1999
- First posted
- Sep 23, 2010
- Registry last updated
- Sep 23, 2010
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Related clinical trials
Published trials that share one or more normalized conditions with this study.
The Psychological Treatment of Overweight Binge Eaters Minority Supplement
NCT01208259
Binge Eating Disorder, Binge-Eating Disorder
New Haven, Connecticut, United States
View Trial DetailsDigital Mindfulness Meditation-enhanced Cognitive Behavioral Therapy (CBT-MM) for Binge Eating Disorder
NCT06604299
Binge Eating Disorder, Binge-Eating Disorder
The Bronx, New York, United States
View Trial DetailsIntegrative Cognitive-Affective Therapy for Binge Eating Disorder
NCT02043496
Binge Eating Disorder, Binge-Eating Disorder
Minneapolis, Minnesota, United States
View Trial DetailsCraving, Binge Eating and Obesity
NCT00414167
Behavior, Binge Eating Disorder
New Haven, Connecticut, United States
View Trial Details