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NCT Number: NCT07521813

Psychiatric Disorders in Dermatiological Diseases

The aim of this study:

1. Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls. 2. Assess the effect of these skin diseases on the quality of life in those children.

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Key information

Age range

6 year–18 year

Sex eligibility

All sexes

Study type

Observational

About this study

Skin diseases are the fourth leading cause of non-fatal disease in humans. Worldwide, between 30% and 70% of individuals are affected. Most dermatological conditions have an impact on patients' social, physical, and emotional well-being, as well as their friends, partners, and families.

The psychological impact of skin diseases is an issue of increasing concern worldwide but little research or exploration in this area has been undertaken.Pediatric psychodermatology is an emerging field that is uniquely tailored to the developmental, emotional, and psychosocial needs of children with psychocutaneous conditions.

Body dysmorphic disorder (BDD) is a psychiatric condition defined as a preoccupation with a perceived defect or flaw in one's physical appearance when, in fact, they appear normal. BDD falls under the spectrum of obsessive-compulsive and related disorders.

Often under recognized, BDD is a prevalent disorder characterized by an all-consuming focus on perceived physical imperfections, leading to distressing repetitive actions and, at times, suicidal behavior and ideation. Individuals with BDD often seek unnecessary surgical interventions.

The affected patients visit dermatology and plastic surgery clinics to repair their perceived defects. Understanding BDD's features and diagnostic criteria across all healthcare specialties helps increase awareness and recognition of the condition.

Body dysmorphic disorder is commonly first encountered by nonpsychiatric physicians. It is estimated to range from 0.7% to 2.4% in general clinics met diagnostic criteria for BDD, increasing to 9% to 12% in general dermatology clinics, 8% to 37% in cosmetic dermatology clinics, 2.9% to 53.6% in cosmetic surgery clinics and 14.1% among patients with chronic skin disease. These findings highlight the strong link between skin disorders and BDD, supporting the importance of studying this link specially in children and adolescents.

Most research on BDD focuses on adolescents and adults, however childhood- BDD remain underestimated because appearance concerns may be misinterpreted as normal developmental features. Children with early symptoms may hide their worries or struggle to express them, contributing to diagnostic delay.

Chronic pediatric dermatological diseases including atopic dermatitis, psoriasis, vitiligo, alopecia areata, and acne vulgaris are associated with a significant psychological burden. Commonly reported psychiatric manifestations include anxiety, depression, low self-esteem, social withdrawal, and impaired quality of life. More severe comorbidities such as ADHD, obsessive-compulsive disorder, bipolar disorder, psychotic disorders, substance use, eating disorders, and suicidal ideation have also been described.

Screening for BDD by dermatologists is of paramount importance. Dermatologists should ask patients with minimal or non-existing defects about how much time each day they spend in thinking about their defects and how much such concerns cause distress or interfere with functioning. Patients who are concerned and preoccupied with perceived defects, spending at least one hour thinking about them and their concerns lead to functioning impairment or clinically significant distress should be considered for BDD diagnosis.

Given the emerging evidence linking skin diseases with body image disturbances in young populations , It is essential to investigate the prevalence, associated factors, and psychosocial impact of BDD among children with skin disorders. This supports the development of early screening programs and collaborative models between dermatology and child mental health services.Early recognition and intervention may significantly improve both psychological well-being and dermatological treatment outcomes in affected children.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The study will include 250 children of both sexes aged from six up to less than 18 years presenting with various chronic skin diseases, diagnosed clinically, by dermoscopy and by biopsy if needed, and age and sex matched healthy controls.
  • Ability of the child and caregiver to understand and respond to the questionnaires.

Exclusion criteria

  • Children with diagnosed psychiatric disorders other than BDD (e.g., severe depression, autism spectrum disorder).
  • Children with chronic systemic illness affecting body image or any other debilitating acute , chronic illness or surgical problems e.g.: short stature, hypothyroidism, osteochondral defects and obesity.

Treatment and study plan

Questionnaire and Physical Exam

Other

The Body Dysmorphic Disorder Questionnaire (BDDQ) :

The BDD-Q is a brief, validated self-administered questionnaire that is used to identify patients having symptoms of BDD. It uses close-ended questions and identifies if participants' concerns regarding appearance are a source of preoccupation.

It also identifies the grade of distress or interference with social and occupational functioning caused by these concerns . It has good validity, high sensitivity (100%) and specificity (89- 93%) for screening for BDD .

BDD diagnosis is likely if answers to question (1) (preoccupation) are yes to both parts, answers to question 3 (significant stress) include yes to any of the questions and answers to question (4) (time spent thinking about defect) include b or c choices.

Primary outcomes

  1. Evaluation of Body Dysmorphic Disorder in Children with Dermatological Diseases

    Time frame: From Apri 2026 to April 2027

    Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls.

    The study will include 250 children of both sexes aged from six to less than 18 years presented with various chronic skin diseases, diagnosed clinically , by dermoscopy and by biopsy if needed, and 250 age and sex matched healthy controls .

    Assessment of the severity of the dermatological diseases according to available valid severity scores will be done .

    Body Dysmorphic Disorder Questionnaire Dermatology Version will be done to identify symptoms of body dysmorphic disorder with valid standardized arabic version .

    The body dysmorphic disorder questionnaire is a brief, validated questionnaire used to identify patients having symptoms of BDD. It uses close-ended questions and identifies if participants' concerns regarding appearance are a source of preoccupation and identifies the grade of distress or interference with social and occupational functioning .

  2. Assess the effect of skin diseases on the quality of life of children

    Time frame: From April 2026 to April 2027

    Assess the effect of skin diseases on the quality of life in children by using Children's Dermatology Life Quality Index questionnaire (CDLQI) that used to evaluate the psychosocial impact of skin disease with valid standardized Arabic version .

    The study will include 250 children of both sexes aged from six up to less than 18 years presenting with various chronic skin diseases, diagnosed clinically, by dermoscopy and by biopsy if needed, and 250 age and sex matched healthy controls then Children's Dermatology Life Quality Index questionnaire (CDLQI) will be assessed with a valid standardized Arabic version .

    The Children's Dermatology Life Quality Index (CDLQI) is a validated questionnaire to assess the impact of skin diseases on the quality of life of children. It evaluates the effect of dermatological conditions on physical symptoms, emotional well-being, daily activities, social interactions, school performance, and treatment.

Study contacts

Contact information is provided by the study sponsor or research team.

Aya Abdelhaseb Abdellatif, Resident doctor

CONTACT

[email protected]

00201142639444

Zeinab Abuelbaha Gouda, Lecturer

CONTACT

[email protected]

00201025863400

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Evaluation of Body Dysmorphic Disorder in Children With Dermatological Diseases

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 13, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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