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NCT Number: NCT06486506

Proximal Femur Reconstruction Following Resection of Primary Bone Tumors: Analysis of the Clinical and Radiographic Results

From the archives of the Rizzoli institute all the patients (approximately 150 patients) undergoing oncological reconstruction of proximal femur from 01/01/1991 to 31/12/2023.

A review will be made from the medical records, radiological imaging, and histological data of these patients

Recruiting

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Key information

Conditions

Bone Tumor Bone Cancer Bone Diseases Bone Neoplasms Musculoskeletal Diseases Neoplasms Neoplasms by Site

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

IRCCS Itituto Ortopedico Rizzoli

Bologna, BO, 40136, Italy

Location status: Recruiting

Location contact

Costantino Errani, MD

CONTACT

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female patients surgically treated with an oncological reconstruction of the proximal femur at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2023
  • Age: 18-90 years old (at the time of primary surgery)
  • Diagnosis of bone sarcoma
  • Patients with available clinical and imaging data

Exclusion criteria

  • At least one inclusion criterion not met

Treatment and study plan

Analysis

Other

Analysis and review of imaging and clinical data

Primary outcomes

  1. longevity of the reconstruction

    Time frame: At baseline (Day 0)

    evaluation of the longevity of the reconstruction, meaning reconstruction failure-free survival after surgery

Secondary outcomes

  1. Musculoskeletal tumour society (MSTS) functional evaluation

    Time frame: at baseline (day 0)

    The MSTS questionnaire consists of six domains, each scored on a scale from 0 to 5, with a higher score indicating better function.

Study contacts

Contact information is provided by the study sponsor or research team.

Costantino Errani, MD

CONTACT

[email protected]

0516366 ext. 103

Roberta Laranga, PhD

CONTACT

[email protected]

051636 ext. 5123

Sponsors and collaborators

Lead sponsor

Costantino Errani

Other

Registry information

Acronym: ProFemuRe

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jul 3, 2024
Registry last updated
May 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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