Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments

This study is a single-center prospective observational study. It plans to use a series of physiological and medical instruments and international common physiological and psychological questionnaires. To dynamically detect the changes of physiological and psychological adaptability of doctors in Peking Union Medical College Hospital before leaving Beijing, 1-7 days after arriving at the plateau in Tibet during the acute phase of plateau hypoxic stress, 2 weeks, 3 months, 6 months, 12 months after staying in Tibet during the chronic phase of plateau hypoxic stress, and after returning to Beijing.

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Key information

Conditions

High Altitude Altitude Sickness Respiration Disorders Respiratory Tract Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Peking Union Medical College Hospital

Beijing, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy individuals aged 20-65 years
They can sign a written informed consent and is willing to cooperate
They have the qualification to aid Tibet and meet the basic requirements of physical examination for aid to Tibet

Exclusion criteria

Age less than 20 years or more than 65 years
Unable to sign a written informed consent or unwilling to cooperate
They do not have the qualification for supporting Tibet or do not meet the basic requirements of medical examination for supporting Tibet

Treatment and study plan

Measurement

Other

Measurement of multiple physiological indicators and psychological status and multi-omics study

Primary outcomes

help understand the physiological mechanisms and psychological changes of hypoxic adaptation

Time frame: 2024-5-27~2026-12-1

This study is expected to increase our understanding of the physiological mechanisms and psychological changes of hypoxic adaptation mainly through analysis of multi-omics.

Sponsors and collaborators

Lead sponsor

Peking Union Medical College Hospital

Other

Registry information

Official study title

Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments: A Clinical Study of Doctors From Peking Union Medical College Hospital

Important dates

Study start: 2024
Primary completion: 2026
Study completion: 2027
First posted: Aug 16, 2024
Registry last updated: Aug 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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