Proteome- and Methylation Profiles in Oropharyngeal Cancer

This clinical study aims to evaluate proteome- and methylation profiles in saliva in patients with oropharyngeal cancers

Completed

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Key information

Conditions

Oropharynx Cancer Head and Neck Neoplasms Neoplasms Neoplasms by Site Oropharyngeal Neoplasms Otorhinolaryngologic Diseases Otorhinolaryngologic Neoplasms Pharyngeal Diseases Pharyngeal Neoplasms Stomatognathic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Otolaryngology - Head and Neck Surgery

Aalborg, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Cancer group:

Inclusion criteria

Written informed consent
Verified oropharyngeal squamous cell carcinoma

Exclusion criteria

Other active cancer
Uncontrolled comorbidity
Unable to give informed consent

Control group:

Inclusion criteria

Written informed consent
Normal ENT examination

Exclusion criteria

Active cancer
Uncontrolled comorbidity
Unable to give informed consent

Treatment and study plan

Examination of saliva

Diagnostic Test

Collection of saliva samples

Primary outcomes

Differences in proteome and methylation profiles

Time frame: At diagnosis

Differences between cancer- and control group

Sponsors and collaborators

Lead sponsor

Aalborg University Hospital

Other

Registry information

Acronym: PROMEO

Important dates

Study start: 2020
Primary completion: 2024
Study completion: 2024
First posted: Sep 28, 2020
Registry last updated: May 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed