Recruiting

NCT Number: NCT01094327

Proteinuria in Pre and Post Transplant

Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.

Recruiting

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Key information

Conditions

Proteinuria Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Glomerulonephritis Glomerulosclerosis, Focal Segmental Kidney Diseases Male Urogenital Diseases Nephritis Pathological Conditions, Signs and Symptoms Signs and Symptoms Urination Disorders Urogenital Diseases Urologic Diseases Urological Manifestations

Age range

Up to 25 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Miami Miller School of Medicine Transplant Clinic

Miami, Florida, 33136, United States

Location status: Recruiting

Location contact

George Burke, M.D.

CONTACT

[email protected]

305-355-5111

George Burke, M.D.

PRINCIPAL_INVESTIGATOR

About this study

This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Kidney transplant recipients
Pediatric males and females up to the age of 25 years old.

Exclusion criteria

Transplant recipients other than kidney

Treatment and study plan

Primary outcomes

Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant

Time frame: through study completion, an average of 5 years

chart review

Study contacts

Contact information is provided by the study sponsor or research team.

George Burke, M.D.

CONTACT

[email protected]

305-355-5111

Lissett Moni

CONTACT

[email protected]

305-243-5235

Sponsors and collaborators

Lead sponsor

University of Miami

Other

Registry information

Official study title

Evaluation of Recipients With and Without Proteinuria, Pre and Post Kidney Transplantation

Important dates

Study start: 2008
Primary completion: 2026
Study completion: 2026
First posted: Mar 26, 2010
Registry last updated: Nov 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting