Protein Ingestion and Muscle Carnitine Uptake

The purpose of this study is to assess the effects of a protein-carbohydrate beverage on the absorption of an orally ingested bolus of L-carnitine, compared to flavoured water and carbohydrate-only controls, and to determine whether increasing plasma carnitine availability can impact upon insulin-stimulated muscle carnitine uptake.

Completed

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Key information

Conditions

Muscle, Skeletal

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 1

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy
Body mass index of 18-25 kg/cm2

Exclusion criteria

Unhealthy
Smoker
Taking any medication that interferes with skeletal muscle metabolism

Treatment and study plan

Flavoured water

Dietary Supplement

Flavoured water + carbohydrate

Dietary Supplement

Flavoured water + carbohydrate + protein

Dietary Supplement

Primary outcomes

Muscle carnitine uptake

Time frame: 180 minutes

Change in forearm carnitine uptake (measured using arterialised-venous - venous balance technique) in response to intervention.

Sponsors and collaborators

Lead sponsor

University of Nottingham

Other

Registry information

Official study title

The Effects of an Insulinotropic Protein-carbohydrate Beverage on L- Carnitine Absorption and Muscle Carnitine Uptake

Important dates

Study start: 2013
Primary completion: 2014
Study completion: 2014
First posted: Aug 31, 2015
Registry last updated: Aug 31, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed