Skip to main content
OpenTrials
Completed

NCT Number: NCT05507801

Protein and Satiety in Older Adults (PROSAT)

This study aims to assess the effect of protein on appetite, food intake and gastric emptying in older adults (≥ 65 years) that are more and less active.

Completed

Looking for future studies?

Notify Me

Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Reading

Reading, United Kingdom

About this study

To investigate the differences in food intake in older adults that are more or less active and assess any differential responses to protein intake.

To compare the effect of meals with high or low protein level but equal in energy and volume on appetite and gastric emptying in older adults that are more or less active (≥ 65 years).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy
  • aged ≥ 65 years

Exclusion criteria

  • having diabetes or disability or any disease that are likely to influence physical activity or appetite.
  • having an allergy to any of the test foods;
  • disliking or cannot eat any of the test foods;
  • being obese (BMI > 30 kg/m2);
  • taking medications known to influence appetite, food intake or body weight in the past three months;
  • being on a weight loss diet;
  • smoking more than 10 cigarettes a day;
  • not meeting the cut-off point criteria based on the accelerometer data (108.25 ≤ min/per day of moderate and vigorous activity for women or 162 ≥ min/per day moderate and vigorous activity for women and 100.1 ≤ min/per day of moderate and vigorous activity for men or 133.25 ≥ min/per day moderate and vigorous activity for men).

Treatment and study plan

High Protein Milkshake

Other

A milkshake with high protein level; including whey protein, fat free strawberry yogurt and whole milk - 337 kcal, 27 g carbohydrate, 57 g protein, 16 g fat.

Normal Milkshake

Other

A milkshake with normal protein level; including nesquik (strawberry), fat free strawberry yogurt, whole milk, double cream, whey protein and sweetener - 331 kcal, 64 g carbohydrate, 17 g protein, 19 g fat.

Primary outcomes

  1. Ad-libitum meal consumption

    Time frame: 2 days in total

    Consumption of the ad-libitum meal is measured (g). Participants are instructed to eat until they feel comfortable full and are given 20 min to consume the meal.

Secondary outcomes

  1. Ratings of appetite

    Time frame: 2 days in total

    Appetite are assessed using a 100 mm Visual Analogue Scales (VAS, scale 0-100).

  2. Gastric Emptying

    Time frame: 2 days in total

    Gastric emptying is measured using of 100 microliters of 13C Octanoic Acid breath test

  3. Ratings of palatability

    Time frame: 2 days in total

    Palatability ratings are assessed using a 100 mm Visual Analogue Scales (VAS, scale 0-100).

Sponsors and collaborators

Lead sponsor

University of Reading

Other

Collaborators

  • Ministry of National Education, Turkey

Registry information

Official study title

The Effect of Protein on Appetite and Food Intake in More and Less Active Older Adults.

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Aug 19, 2022
Registry last updated
Jun 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.