Prospective Ultrafast MRI Radiomics for Breast Cancer

The goal of this prospective study is to investigate the performance of ultrafast MRI radiomics in classifying histological factors and subtypes of breast cancer compared with standard MRI among radiologists with varying experience. The written informed consent was obtained from all participant. We extracted 1618 radiomic features from ultrafast and standard contrast-enhanced MRI before treatment. Classification of hormonal receptors, human epidermal growth factor receptor 2, and Ki67 status and subtypes was evaluated using the area under the receiver-operating characteristic curve (AUC) with the DeLong test.

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Key information

Conditions

Breast Cancer Breast Diseases Breast Neoplasms Neoplasms Neoplasms by Site Skin Diseases Skin and Connective Tissue Diseases

Age range

27 year–86 year

Sex eligibility

Female

Study type

Observational

Primary location

Bo Kyoung Seo

Ansan, 15355, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed with invasive breast cancer

Exclusion criteria

Diagnosed with other cancer

Treatment and study plan

MRI

Diagnostic Test

MRI based classification of breast cancer histological factors and subtypes

Primary outcomes

The signal intensity of MRI according to histological factors and subtypes of breast cancer

Time frame: Baseline, pre-surgery

Quantitative image values obtained from ultrafast MRI show similar performance in classifying histological factors and subtypes compared with standard MRI.

Sponsors and collaborators

Lead sponsor

Korea University Ansan Hospital

Other

Registry information

Official study title

Ultrafast MRI Radiomics to Classify Histological Factors and Subtypes of Breast Cancer

Important dates

Study start: 2021
Primary completion: 2022
Study completion: 2023
First posted: Oct 27, 2023
Registry last updated: Oct 27, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed