Prospective Study of the Impact of Systemic Corticosteroid Use on Measures of Sleep Disordered Breathing

Weight gain is both a significant risk factor for obstructive sleep apnea and a side-effect of long-term systemic steroids therapy.

This study aimed to investigate the impact of long-term systemic steroid treatment on sleep apnea.

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Key information

Conditions

Sleep Apnea Apnea Dyssomnias Nervous System Diseases Respiration Disorders Respiratory Tract Diseases Sleep Apnea Syndromes Sleep Disorders, Intrinsic Sleep Wake Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Rambam health care campus

Haifa, 31096, Israel

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

For inclusion, a scheduled therapy with a minimum daily dose of 10 mg prednisone (or equivalent) for at least 3 months was required

Exclusion criteria

Patients younger than 18 years and those with known sleep apnea or other forms of sleep-disordered breathing were excluded

Treatment and study plan

Sleep Study

Other

The polysomnography (PSG) (Alice 3 System; Healthdyne, Atlanta, GA) consisted of continuous polygraphic recording from surface leads for electroencephalography, electrooculography, electromyography, electrocardiography, thermistors for nasal and oral airflow, thoracic and abdominal impedance belts for respiratory effort, pulse oximeter for oxyhemoglobin level, tracheal microphone for snoring, and sensors for leg and sleep position

Other names: no other names

Primary outcomes

apnea-hypopnea index

Time frame: 3 months

Secondary outcomes

sleep study variables

Time frame: 3 months

apnea-hypopnea interval desaturation at the end of apnea interval snoring intensity

Sponsors and collaborators

Lead sponsor

Rambam Health Care Campus

Other

Collaborators

Israeli association for lung disease

Registry information

Important dates

Study start: 2007
Primary completion: 2010
Study completion: 2010
First posted: Oct 26, 2010
Registry last updated: Oct 26, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed