Prospective Study for Neuromelanin Image Analysis

Parkinsin group

Inclusion criteria

• Adults over 19 years old
• Those who have clinically shown Parkinson's symptoms such as tremor, Rigidity, Bradykinesa and gait disturbance and are scheduled to take MRI scans
• Dopamine transporter imaging shows a significant decrease in visual dopamine intake
• A person who can read and understand the description and informed consent form
• Upon hearing and fully understanding the detailed explanation of this clinical trial, a person who has voluntarily decided to participate and agreed in writing to comply with the precautions

Exclusion criteria

• Patient with a history of claustrophobia and mental illness;
• Patient with metallic substances in the body
• Any female subject who is likely to be pregnant who does not agree to contraception in a medically permitted manner during this clinical trial period
• Pregnant or lactating women
• Other cases where the investigator judged that it is difficult to participate in the study;

Healthy volunteer group

Inclusion criteria

• Adults over 19 years old
• A person who has no family history or diagnostic history of movement disorders;
• A person with a score of 8 or higher on the CCSIT(cross cultural smell identification test)
• A person with a score of 27 or higher on the MMSE Test
• No Parkinson's symptoms on a neurological examination
• Upon hearing and fully understanding the detailed explanation of this clinical trial, a person who has voluntarily decided to participate and agreed in writing to comply with the precautions

Exclusion criteria

• Patient with a history of central nervous system disease or cognitive disorder
• Patient with a history of claustrophobia and mental illness;
• Patient with metallic substances in the body
• Any female subject who is likely to be pregnant who does not agree to contraception in a medically permitted manner during this clinical trial period
• Pregnant or lactating women
• Other cases where the investigator judged that it is difficult to participate in the study;