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Recruiting

NCT Number: NCT04755855

Prospective Sinonasal Cancer Multi-institution Study

This is a multi-institution prospective study of patients with sinonasal malignancies. The goal of this study is to learn more about the course of sinonasal cancer, treatment outcomes, and patient quality of life. In addition, central mutational and genomic analysis of tumor tissue will be evaluated.

Recruiting

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Key information

Conditions

Sinonasal Carcinoma

Age range

30 day–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location status: Recruiting

Location contact

Clinical Trials Referral Office

CONTACT

[email protected]

855-776-0015

Jake Eide, MD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects between the ages of 30 days (non-inclusive) and 99 years (inclusive)
  • Patients with a diagnosis of sinonasal cancer
  • Patients undergoing treatment at Mayo Clinic

Exclusion criteria

  • Healthy individuals
  • Unwilling to sign the informed consent

Treatment and study plan

Primary outcomes

  1. Oncologic outcomes as measured by overall survival, disease specific survival and recurrence free survival

    Time frame: Through study completion, an average of 5 years

Secondary outcomes

  1. Quality of life outcomes including the University of Washington Quality of Life Questionnaire (UW-QOL v4) and the Sinonasal Outcome Test 22 (SNOT22)

    Time frame: Through study completion, an average of 5 years

  2. Describe the molecular foundation of sinonasal malignancies utilizing RNA sequencing to identify transcriptomic tumor profiles

    Time frame: Through study completion, an average of 5 years

Study contacts

Contact information is provided by the study sponsor or research team.

Clinical Trials Referral Office

CONTACT

[email protected]

855-776-0015

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Sinonasal Cancer Study to Evaluate Oncologic Outcomes and Quality of Life

Important dates

Study start
2021
Primary completion
2031
Study completion
2031
First posted
Feb 16, 2021
Registry last updated
Apr 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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