Prospective Registry Of Therapeutic EndoscopiC ulTrasound

This is an observational, prospective, single centre study. This registry aims to evaluate long-term clinical success of EUS-guided therapeutic interventions (T-EUS), as well as adverse events, and clinical and technical variables asociated with clinical success and adverse events.

For the purpose of this registry, the following procedures will be considered to be T-EUS procedures:

• EUS-guided collection drainage
• EUS-guided biliary drainage
• EUS-guided gallbladder drainage
• EUS-guided gastro-enterostomy
• EUS-directed ERCP
• EUS-guided pancreatic duct drainage

Each patient will be assigned to a procedure following standard clinical practice, in most instances following a routinely multidisciplinary discussion.

Patients eligible for the abovementioned clinical indications, but undergoing alternative procedures (e.g. other endoscopic procedures, surgical interventions or percutaneous interventions) will be enrolled in the registry as "controls" according to specific research questions.

The same variables will be collected, with the exception of technical variables related to the EUS-guided intervention.

Inclusion criteria

• subjects candidate to therapeutic EUS (T-EUS) procedures for any underlying disease
• subject eligible to T-EUS procedures but undergoing other non-EUS based endoscopic procedures, percutaneous or surgical procedures
• 18 years old or older
• able to provide an informed consent to inclusion.

Exclusion criteria

• age < 18 years
• inability or unwillingness to sign the informed consent form (ICF)
• contra-indication for endoscopy or use of fluoroscopy