Skip to main content
OpenTrials
Recruiting

NCT Number: NCT04559919

Prospective Regional Epilepsy Database

PREDICT is an observational study following adults with an unprovoked seizure or epilepsy in the health care region of western Sweden. The objective is to identify biomarkers and/or genetic predisposition of relevance for diagnosis and/or treatment of epilepsy and study the long-term prognosis and consequences of epilepsy.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Epilepsy Brain Diseases Central Nervous System Diseases Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Seizures Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Södra Älvsborgs Sjukhus, Borås, Sweden

Loading trial locations.

About this study

Adults over 18 years of age, with an unprovoked seizure in the last year or epilepsy, resident in the health care region of western Sweden (VGR) at the time of inclusion.

Baseline data and outcome variables are collected from several patient registries: the electronic medical records system in the health care region VGR and Swedish National Registers of healthcare, income, and employment managed by The National Board of Health and Welfare or Statistics Sweden, both of which are government agencies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Over 18 years of age
  • An unprovoked seizure within the last year or a diagnosis of epilepsy according to the current International League Against Epilepsy definition (epilepsy with seizure in the last ten or antiepileptic drug treatment in the last five years)

Exclusion criteria

  • Expected survival less than two years
  • Inability to give informed consent

Treatment and study plan

Seizure status

Other

We will collect information on first seizure ever, last seizure ever, number of seizure in last two months.

Tests

Diagnostic Test

We will collect results from imaging, electroencephalogram, and laboratory tests.

Epilepsy

Other

We will collect information on risk factors of epilepsy, cause of epilepsy, epilepsy type/syndrome, medications tried, if the epilepsy is drug resistent, side effects of antiepileptic drugs.

Demographics and psychosocial

Other

We will collect information on age, sex, date of death if applicable, marital status, education level, income type, driving status, employment, benefits, sick leave, number of household members.

Health care

Other

We will collect information on received health care; visit dates, caregiver, dispensation dates of antiepileptic drugs

Primary outcomes

  1. epilepsy

    Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10

    more than one seizure after first seizure

  2. seizure status

    Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10

    the number of seizures in last two months and overall

  3. drug resistant epilepsy

    Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10

    epilepsy that has not responded to two antiepileptic drugs

  4. severe side effects of antiepileptic drug

    Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10

  5. psychosocial outcomes

    Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10

    employment, marital status, income, sick leave

Secondary outcomes

  1. received health care

    Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10

    the number of visits for epilepsy, missed appointments, time intervals between visits

Study contacts

Contact information is provided by the study sponsor or research team.

Johan Zelano, MD PhD

CONTACT

[email protected]

+46313421000

Sponsors and collaborators

Lead sponsor

Sahlgrenska University Hospital

Other

Registry information

Official study title

Prospective Regional Epilepsy Database and Biobank for Individualized Clinical Treatment

Acronym: PREDICT

Important dates

Study start
2020
Primary completion
2031
Study completion
2031
First posted
Sep 23, 2020
Registry last updated
Jun 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.