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NCT Number: NCT02011932

Prospective Observational Study of Disease Progression in Chronic Hepatitis C

The purpose of this study is to determine the progression of chronic hepatitis C patients infected by paid plasma donation,and explore the possible pathogenic mechanisms of disease progression in chronic hepatitis C.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Hepatitis C, Chronic Blood-Borne Infections Chronic Disease Communicable Diseases Digestive System Diseases Disease Attributes Disease Progression Fibrosis Flaviviridae Infections Hepatitis Hepatitis C Hepatitis, Chronic Hepatitis, Viral, Human Infections Liver Cirrhosis Liver Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms RNA Virus Infections Virus Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All these patients had a definite history of regular plasma donations with repeated blood cell re-transfusions.
  • The Hepatitis C Virus antibody was positive.
  • All patients did not receive interferon therapy before being recruited.

Exclusion criteria

  • Patients with evidences for other forms of liver diseases.
  • The coinfection with hepatitis B virus or other virus.

Treatment and study plan

Primary outcomes

  1. Fibrosis progression rate

    Time frame: 20 years

  2. The incidence of cirrhosis

    Time frame: 20 years

  3. Risk factors for the occurrence of cirrhosis

    Time frame: 20 years

Secondary outcomes

  1. The incidence of hepatocellular carcinoma

    Time frame: 20 years

  2. Number of participants with chronic hepatitis C-related complications

    Time frame: 20 years

Sponsors and collaborators

Lead sponsor

Beijing YouAn Hospital

Other

Registry information

Official study title

Observational Study of Disease Progression and Risk Factors in Chronic Hepatitis C Caused by Plasma Donation

Important dates

Study start
2010
Primary completion
2011
Study completion
2030
First posted
Dec 16, 2013
Registry last updated
Dec 17, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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