University Hospitals of North Midlands NHS Trust
Stoke-on-Trent, United Kingdom
NCT Number: NCT06376461
Part A Multiple organ dysfunction syndrome is one of the main problems in critically ill patients. Several organ dysfunctions are routinely and systematically monitored in patients admitted to intensive care units. Gastrointestinal dysfunction is currently not included in multiple organ dysfunction scores and lacks a standardised approach. At the same time, investigators earlier studies have shown that gastrointestinal dysfunction plays an essential role in the course of illness in intensive care patients. A tool for measuring dysfunction is needed to enable future studies on interventions to improve gastrointestinal function. The GIDS (GastroIntestinal Dysfunction Score) combines different clinical signs and symptoms commonly observed and documented in patients in the ICU into a scoring system, allowing distinguishing between different grades of severity of dysfunction. The investigators will only use observations documented during the patient's stay in the intensive care unit without additional measurements and calculate gastrointestinal (GIDS) and other organ dysfunction scores.
Part B Phosphate is an electrolyte commonly measured and often corrected, while the indications and clear guidance for correction are insufficiently studied. The results of this study will assist in specifying indications for the correction of phosphate levels better and refine the management strategies in the future. Only phosphate levels measured as part of routine care will be documented, no additional samples for study purposes will be taken, and the study will not influence the treatment of phosphate disorders.
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Notify Me18 year and older
All sexes
Observational
Stoke-on-Trent, United Kingdom
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Sites will recruit all consecutive adult patients admitted to ICU, to a maximum of 120 patients or a maximum recruitment period of 8 weeks, whichever comes first
Time frame: 28 days after ICU admission
28 day all cause mortality
Time frame: 90 days after ICU admission
90 day all cause mortality
Time frame: 28 days after admission to ICU
ICU length of stay/days alive and free of ICU by day 28
Time frame: 90 days after admission to ICU
ICU length of stay/days alive and free of ICU by day 90
Time frame: 28 days after admission
Hospital length of stay/days alive and free of hospital by day 28
Time frame: 90 days after admission
Hospital length of stay/days alive and free of hospital by day 90
Time frame: 28 days after admission
Days alive and free of organ support (including PN free days) by day 28
University Hospitals of North Midlands NHS Trust
Other
Acronym: GUTPHOS
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