Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome

Create a multicenter prospective registry that collects information from women affected by acute coronary syndrome (ACS) from a wide range of cultural and ethnic backgrounds distributed across various Italian regions. This registry aims to understand the diversity in the presentation of women with ACS in Italy, providing valuable data for a better understanding of the disease.

Additionally, it proposes to conduct a thorough characterization of the women involved in the study through genetic, biochemical, and molecular analysis. This analysis will be stratified by age and the etiology of coronary artery disease, distinguishing between obstructive and non-obstructive coronary artery disease.

Specific aims of this proposal are:

• To create a multicenter prospective registry including women with ACS from a variety of cultural and ethnical backgrounds in different Italian regions
• To deeply characterize women with ACS through clinical, imaging, genetic, biochemical, and molecular phenotyping stratifying for age, etiology (obstructive vs non-obstructive CAD) and diversity.
• To assess socioeconomic status, health literacy and awareness of risk factors among enrolled patients.

Inclusion criteria

• Women >/= 18 years with ACS (STEMI, NSTEMI or Unstable Angina).

Exclusion criteria

• age < 18 years and/or unwillingness to sign informed consent and/or unwillingness to make follow-up visits