The University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
Enrolling by Invitation
NCT Number: NCT07456137
Prospective Evaluation of Upright Versus Supine CT Myelography of the Lumbar Spine
The purpose of this prospective study is to compare the diagnostic utility of standing (upright, weight-bearing) CT myelography with standard supine CT myelography for the evaluation of lumbar central canal and neural foraminal stenoses. This study aims to determine whether upright positioning provides additional diagnostic information in patients unable to undergo MRI, with the goal of improving assessment and management of degenerative lumbar spine disease.
Enrolling by Invitation
Interested in participating?
Request InfoKey information
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Age ≥ 18 years
- Outpatient status
- Scheduled for routine supine CT myelography
Exclusion criteria
- Inpatient status
- Presence of metallic lumbar spinal hardware
- History of osseous metastatic disease involving the lumbar spine
- Acute traumatic injury involving the lumbar spine
- Pregnancy
- Participant body habitus exceeding the scanner's safe operational limits (e.g., gantry/bore size clearance, table weight capacity) as defined by the device manufacturer.
- Inability to tolerate CT scanning (e.g., severe pain, unable to stand independently for an extended period)
Treatment and study plan
Upright CT
RadiationUpright CT Myelography
Other names: Upright CT Myelography
Primary outcomes
-
Does upright CT imaging change management plans for patients with lumbar spinal stenosis
Time frame: 1 week
To determine whether upright CT imaging changes the management plan (yes or no) for patients with lumbar spinal stenosis.
Secondary outcomes
-
Spine measurements
Time frame: 1 day
Objective measurements at different angles (mm) will be taken of the spine.
-
Severity grading of central canal stenosis
Time frame: 1 day
Severity grading (mild, moderate, severe) of central canal stenosis in the spine.
-
Severity grading of neural foraminal stenosis
Time frame: 1 day
Severity grading (mild, moderate, severe) of neural foraminal stenosis in the spine.
-
Presence or absence of nerve root compression
Time frame: 1 day
Presence or absence of nerve root compression in the spine.
-
Presence or absence of disc bulges
Time frame: 1 day
Presence or absence of disc bulges in the spine.
-
Presence or absence of herniations
Time frame: 1 day
Presence or absence of herniations in the spine.
Sponsors and collaborators
Lead sponsor
University of Kansas Medical Center
Other
Registry information
Important dates
- Study start
- 2026
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Mar 6, 2026
- Registry last updated
- Jul 10, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.