NCT Number: NCT07208578
Prospective Evaluation of Electrical Cardiometry for Hemodynamic Monitoring in COPD Patients Admitted to the Respiratory Intensive Care Unit
This study investigates the reliability and clinical usefulness of non-invasive electrical cardiometry (ICON® device) in monitoring hemodynamic changes in COPD patients admitted to the respiratory intensive care unit (RICU).
Trial opening soon.
Get NotifiedKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
About this study
hemodynamic monitoring is critical in critically ill patients, especially those with COPD experiencing acute respiratory failure. Traditional invasive methods such as pulmonary artery catheterization are accurate but carry procedural risks. The ICON® device enables real-time, continuous, non-invasive assessment of parameters like cardiac output, stroke volume, systemic vascular resistance, and thoracic fluid content using thoracic bioimpedance. This prospective observational study will assess its reliability against clinical outcomes and evaluate the influence of different ventilation strategies (invasive, non-invasive, no ventilation) on hemodynamic changes. Data will be collected serially throughout ICU stay to determine ICON's contribution to optimizing patient management and risk stratification.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Age ≥ 18 years
Admission to RICU with COPD or COPD-related acute respiratory failure
Informed consent provided by patient or legal representative
Exclusion criteria
- patients <18 years
Pregnant women
Injuries, burns, or skin conditions preventing electrode placement
Patients with uncontrolled seizures
Patients needing electrical DC shock
Refusal or withdrawal of informed consent
Treatment and study plan
Primary outcomes
-
Cardiac output (CO) measured by the electrical cardiometer (ICON®) in COPD patients admitted to the respiratory ICU.
Time frame: Baseline
The change in cardiac output values during the ICU stay as measured non-invasively by the ICON device, reflecting hemodynamic status.
Sponsors and collaborators
Lead sponsor
Assiut University
Other
Registry information
Official study title
Non-invasive Hemodynamic Monitoring in COPD Patients Admitted to the Respiratory Intensive Care Unit: Reliability, Clinical Utility, and Ventilation-related Hemodynamic Changes
Important dates
- Study start
- 2026
- Primary completion
- 2027
- Study completion
- 2027
- First posted
- Oct 6, 2025
- Registry last updated
- Oct 6, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.