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Recruiting

NCT Number: NCT06450353

Prospective Evaluation of Disparities in Provision of Allogeneic Transplantation

To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).

Recruiting

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Key information

Conditions

Allogeneic Transplantation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

MD Anderson Cancer Center

Houston, Texas, 77030, United States

Location status: Recruiting

Location contact

Warren Fingrut, MD

CONTACT

[email protected]

832-387-8363

Warren Fingrut, MD

PRINCIPAL_INVESTIGATOR

About this study

Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC.

Secondary Objectives

  • To prospectively evaluate time to transplant for allograft candidates at MDACC.
  • To evaluate treatment-related mortality for allograft candidates at MDACC.
  • To assess overall survival for allograft candidates at MDACC.
  • To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC.
  • To evaluate receipt of an optimal graft for allograft recipients at MDACC.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ≥ 18 years of age.
  • Candidate for allogeneic transplantation

Exclusion criteria

  • Allogeneic stem cell transplantation not medically indicated.

Treatment and study plan

Patient Ancestry Questionnaires

Behavioral

Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.

Primary outcomes

  1. Patient Ancestry Questionnaire

    Time frame: Through study completion; an average of 1 year.

Study contacts

Contact information is provided by the study sponsor or research team.

Warren Fingrut, MD

CONTACT

[email protected]

(832) 387-8363

Sponsors and collaborators

Lead sponsor

M.D. Anderson Cancer Center

Other

Registry information

Important dates

Study start
2024
Primary completion
2027
Study completion
2029
First posted
Jun 10, 2024
Registry last updated
Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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