Skip to main content
OpenTrials
Recruiting

NCT Number: NCT05699629

Prospective Coronary Heart Disease Cohort

To evaluate the biomarkers for the prognosis of coronary heart disease, patients with coronary heart disease will be recruited and followed up for at least 2 years.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Coronary Heart Disease Cardiovascular Diseases Coronary Disease Heart Diseases Infarction Ischemia Myocardial Infarction Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Shandong First Medical University

Jinan, Shandong, 277500, China

Location status: Recruiting

Location contact

Rong Huang, Dr.

CONTACT

About this study

Patients with cardiovascular disease undergoing coronary angiography will be recruited and prospectively followed up for the incidence of major adverse cardiovascular events (MACE events), including all-cause mortality, cardiovascular mortality, ischemic stroke, heart failure and rehospitalization. Blood and fecal samples will be collected for further analysis. The basic and clinical information will be collected such as socio-demographic, diet, lifestyle, psychological status and medical history. The biomarkers for the incidence of coronary heart disease and the factors contributing to the poor prognosis of coronary heart disease will be investigated based on multi-omics analysis.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed as coronary heart disease or with unexplained chest pain needed to undergo coronary angiography.
  • Healthy subjects undergoing routine physical examination in the physical examination department and willing to sign informed consent will be recruited as control subjects.

Exclusion criteria

  • With malignant tumors, infectious diseases and advanced liver diseases.
  • Won't sign an inform consent.

Treatment and study plan

Primary outcomes

  1. major adverse cardiovascular events

    Time frame: 2-year outcome and long-term outcome

    all-cause mortality, cardiovascular mortality, ischemic stroke, heart failure and rehospitalization

Study contacts

Contact information is provided by the study sponsor or research team.

Rong Huang, Dr.

CONTACT

[email protected]

18854125717

Sponsors and collaborators

Lead sponsor

Shandong First Medical University

Other

Collaborators

  • Jinan Central Hospital
  • Qianfoshan Hospital
  • Shandong Provincial Hospital
  • The Second Affiliated Hospital of Shandong First Medical University

Registry information

Official study title

A Prospective Longitudinal Multi-Omics Cohort of Patients With Coronary Heart Disease Undergoing Coronary Angiography

Important dates

Study start
2022
Primary completion
2027
Study completion
2027
First posted
Jan 26, 2023
Registry last updated
Feb 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.