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Recruiting

NCT Number: NCT03117036

Prospective Cohort Study for Lymphoma: Samsung Lymphoma Cohort Study III

This prospective study enrolls patients who are diagnosed with aggressive lymphoma including Hodgkin and non-Hodgkin lymphomas. Enrolled patients will be treated according to our institution' treatment policy in clinical practice. The disease status including response to therapy and survival status will be regularly updated during the study period. Patients' serum and cell-free DNA will be collected and analyzed.

Recruiting

Interested in participating?

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Key information

Age range

20 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Samsung Medical Center

Seoul, 135-710, South Korea

Location status: Recruiting

Location contact

Seok Jin Kim, MD, PhD

CONTACT

[email protected]

82-2-3410-1766

Seok Jin Kim, MD, PhD

PRINCIPAL_INVESTIGATOR

Sivia Park, MD, PhD

SUB_INVESTIGATOR

Won Seog Kim, MD, PhD

SUB_INVESTIGATOR

About this study

The study population is aggressive lymphomas requiring systemic chemotherapy. Newly diagnosed or relapsed/refractory patients can be enrolled into the study. Patients can be treated according to the principle of routine care of our institute. The study process is as follows.

  • Registration after informed consent.
  • Laboratory and radiological evaluation after registration including collection of serum and cell-free DNA from patients' peripheral blood
  • Interim and final response evaluation including collection of serum and cell-free DNA from patients' peripheral blood
  • Regular monitoring disease status and update of survival status
  • Laboratory and radiological evaluation after relapse or progression including collection of serum and cell-free DNA from patients' peripheral blood

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pathologically diagnosed Hodgkin and non-Hodgkin lymphomas
  • 20 years
  • Patients requiring systemic chemotherapy with curative intent
  • Written informed consent

Exclusion criteria

  • Myeloid malignancy
  • Multiple myeloma
  • Patients do not require systemic chemotherapy with curative intent

Treatment and study plan

Chemotherapy

Drug

Systemic chemotherapy with curative intent

Other names: Treatment

Primary outcomes

  1. Response rate

    Time frame: 3 months after chemotherapy

    response to chemotherapy

Secondary outcomes

  1. Progression-free survival

    Time frame: 3 year

    Time to relapse/progression or any kinds of death

  2. Overall survival

    Time frame: 3 year

    Time to any kinds of death

  3. Biomarker

    Time frame: 3 year

    Development of biomarker predicting response and survival outcome

Study contacts

Contact information is provided by the study sponsor or research team.

Seok Jin Kim, MD, PhD

CONTACT

[email protected]

+82234101766

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Collaborators

  • Samsung Genomic Institute

Registry information

Official study title

A Prospective Study for Patients With Lymphoid Malignancy at the Samsung Medical Center

Important dates

Study start
2017
Primary completion
2026
Study completion
2026
First posted
Apr 17, 2017
Registry last updated
May 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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