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NCT Number: NCT07444515

Prospective AnalysiS of Self medIcation With phytOtherapy in Nephropatic Patients.

We propose the following hypotheses:

* The use of herbal medicine is common among patients with chronic kidney disease in Réunion island. * This use could influence the progression of kidney disease in these patients. To assess the primary inclusion criterion, patients will be easily identified by nephrologists through existing follow-up. The questionnaires will be administered after this early identification by the investigators at each center.

The primary evaluation criterion is straightforward: it aims to establish an overview of the use of herbal medicine in our patient population. This information is currently unavailable and remains crucial for measuring the extent of the issue. Our secondary criteria will involve more in-depth analysis of this use and an attempt to correlate the use of certain herbs with the rate of progression of kidney disease at one year.

We targeted patients with moderate to end-stage chronic kidney disease (KDIGO classification 3 to 5), which are the stages typically included in kidney disease studies. Furthermore, these patients are the most likely to experience a greater annual progression of their kidney disease, and the effect of herbs on this progression could be investigated. Transplant patients were not included because they are more aware of the risks of not using herbal medicine due to their use of immunosuppressants.

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Individual:

  • Adult
  • Resident of Réunion Island and planning to remain on the island for the year following enrollment
  • Chronic Kidney Disease Stage 3, 4, or 5, not on dialysis
  • Under the care of a nephrologist
  • Able to complete a questionnaire
  • Registered with social security

Exclusion criteria

Individual:

  • Kidney transplant recipient
  • Adult under guardianship or legal protection
  • Pregnant or breastfeeding women, or women planning a pregnancy during the enrollment period

Treatment and study plan

series of questions which can change patient care

Other

Series of question are about self medication with plants

Primary outcomes

  1. Proportion of patients with stage 3 to 5 CKD using traditional herbal medicine at baseline

    Time frame: baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Hospital promotion

CONTACT

[email protected]

0262359000

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de la Réunion

Other

Registry information

Acronym: PASSION

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Mar 3, 2026
Registry last updated
Mar 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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