Skip to main content
OpenTrials
Completed

NCT Number: NCT01240018

ProSat - Long Term Effect of Probiotics on Satiety

The aim of the ProSat study is to examine the effects of a probiotic capsule containing Lb. Casei on subjective appetite sensation, ad libitum energy intake, and appetite hormone response in a single meal test and to determine whether the acute effects persist after daily supplementation of the probiotic capsule.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Obesity Appetite Regulation Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

University of Copenhagen, Department of Human Nutrition

Frederiksberg, DK, 1958, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy men and women
  • Normal to slight overweight (BMI: 22-28 kg/m2)
  • 20-45 years of age

Exclusion criteria

  • Smoking
  • Daily medicine use (oral contraceptives excluded)
  • Use of pre- and probiotic supplements and foods
  • Blood donation 3 months prior to the study
  • Hb < 7,5mmol/l
  • Chronic illnesses such as hyperlipidemia, diabetes inflammatory diseases
  • Pregnancy or breastfeeding
  • Elite athletes (>10 hours hard exercise/week)
  • Vegetarians

Treatment and study plan

Probiotic

Dietary Supplement

Parallel, randomized, controlled 2 arms study.

Primary outcomes

  1. Glucose, insulin, GLP-1, GLP-2, CCK, PYY, PP, ghrelin, amylin, LPS, TNF-alfa, CRP, fibrinogen.

    Time frame: June 2011

Secondary outcomes

  1. Subjective appetite measurements, spontaneous food intake.

    Time frame: June 2011

Sponsors and collaborators

Lead sponsor

University of Copenhagen

Other

Registry information

Official study title

Probiotics and Satiety - Acute Effects and Persistence of Acute Effects

Acronym: ProSat

Important dates

Study start
2009
Primary completion
2011
First posted
Nov 15, 2010
Registry last updated
Jun 15, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.