Skip to main content
OpenTrials
Completed

NCT Number: NCT00529776

Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Hypothesis: Ventilator associated pneumonia (VAP) in critically ill patients may be prevented by continuous lateral rotation therapy (CLRT) using specially designed, motor driven beds.

Patients are randomized to CLRT or supine position if mechanically ventilated and not suffering from pneumonia or ARDS within 48 hours after intubation. Prophylaxis of VAP is standardized in both groups. Primary endpoint is incidence of VAP, secondary endpoints are length of ventilation, length of stay and mortality.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pneumonia, Ventilator-Associated Cross Infection Disease Attributes Healthcare-Associated Pneumonia Iatrogenic Disease Infections Lung Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Respiratory Tract Diseases Respiratory Tract Infections

Age range

18 year–89 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Vienna General Hospital, Medical University of Vienna

Vienna, 1090, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Mechanically ventilated
  • Intubated not longer than 48 h
  • Medical cause for ICU admission
  • Expected to be ventilated for > 48 hours

Exclusion criteria

  • Pneumonia or ARDS present
  • Postoperative patient

Treatment and study plan

Continuous lateral rotation therapy

Procedure

Primary outcomes

  1. Ventilator associated pneumonia

Secondary outcomes

  1. Length of hospital stay

  2. Length of mechanical ventilation

  3. ICU and hospital Mortality

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Important dates

Study start
2005
Study completion
2008
First posted
Sep 14, 2007
Registry last updated
Jun 11, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.