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OpenTrials
Completed

NCT Number: NCT07433439

Prophylactic Mesh Placement Reduces the Incidence of Incisional Hernia in HBP Surgery.

he goal of this observational study is to learn about prophylactic mesh placement in HBP incision. The main question it aims to answer is:

will the incisional hernia rate be reduced with the use of mesh during the abdominal wall closuer?

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Key information

Conditions

Hernia Incisional Hernia Incision Site Complication Incisional Hernia Pathologic Processes Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Postoperative Complications

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Juan Bellido

Seville, Spain

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 years or older.
  • Elective conventional or extensive right subcostal laparotomy.
  • Two or more risk Factor for incisional hernia (IH): > 60 years, Body Mass Index > 27 kg/m2, Diabetes Mellitus, pulmonary/liver/renal disease, malignancy, preoperative chemotherapy, immunosuppression or smoking5.
  • Life expectancy of at least 12 months.
  • Signed informed consent with agreement to attend all study visits.

Exclusion criteria

  • Emergency surgery.
  • Previous right subcostal hernia or right subcostal incision.
  • Metastatic disease or irresectable malignancy identified during the surgery with life expectancy less than 12 months.
  • Active abdominal infection at the time of surgery

Treatment and study plan

mesh placement

Procedure

mesh is placed in retromuscular space when abdominal wall is closed

conventional abdominal wall closure without mesh

Other

conventional AWC without mesh

Primary outcomes

  1. image detected IH rate

    Time frame: 12 and 24 months

    incisional hernia rate after 12 and 24 posoperative months

Secondary outcomes

  1. incision types

    Time frame: day 1 (surgical procedure)

    types of incisions used

  2. postoperative complications

    Time frame: 3-6-12-24 postoperative months

    complications after surgical procedure

Sponsors and collaborators

Lead sponsor

Juan Bellido-Luque.MD

Other

Collaborators

  • Hospital Universitario Virgen Macarena

Registry information

Acronym: meshproph

Important dates

Study start
2020
Primary completion
2024
Study completion
2025
First posted
Feb 25, 2026
Registry last updated
Feb 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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