Skip to main content
OpenTrials
Completed

NCT Number: NCT01899781

Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon

The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hand Laceration Clean Laceration Lacerations No Bone Involved Tendon Involved Wounds and Injuries

Age range

13 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

About this study

Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.

prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hand laceration
  • Tendon involeved
  • Clean laceration
  • No bone involved

Exclusion criteria

  • Pregnant
  • Children
  • Immunocompremised patients
  • "Dirty" lacerations

Treatment and study plan

Antibiotic-Cefamezin

Drug

Other names: Ceforal, Keflex

Primary outcomes

  1. rate of wound infections

    Time frame: 2 years

    signs of wound/tissue infection, levels of WBC, ESR, CRP

Sponsors and collaborators

Lead sponsor

HaEmek Medical Center, Israel

Other

Registry information

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Jul 15, 2013
Registry last updated
Feb 17, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.