Ceftriaxone 2000 mg
Drugantibiotic prophylaxis
Other names: ceftriaxone
NCT Number: NCT06527989
Assessment of surgical site infection when using postoperative antibiotic prophylaxis in subtalar fusion surgery 24hours versus 5 days
Trial opening soon.
Get Notified18 year–60 year
All sexes
Interventional
Phase 2 / Phase 3
Infection in orthopedic surgery is one of the most dreaded complications. Antibiotic prophylaxis should be utilized routinely in foot and ankle surgeries involving bone, utilizing hardware and prosthetic joints.
It is appropriate for the antibiotics to be administered within 60 minutes prior to surgery, discontinued within 24 hours after surgery, given prior to tourniquet inflation, and utilized routinely in prolonged foot and ankle surgery cases.
Narrow spectrum antibiotics covering Staphylococcus aureus should be utilized for prophylaxis in patients without a history of resistant infection. According to American Society of Health System Pharmacists (ASHP) cefazolin was the most used antibiotic in preoperative prophylaxis, combination of cefazolin with gentamicin was the second common regimen while 3rd generation cephalosporin were 3rd widely used antibiotics.
The controversy persists in administration of antibiotics varying from a single dose to 3 doses to 5 days or 14 days. In subtropical country, with a hot and humid climate is a conducive environment for both Gram-positive and Gram-negative bacterial colonization of skin. Therefore, we need studies tailored to our environment in Egypt Prevention of SSIs is critical for the health of patients, Economic efficiency, Antibiotic resistance considerations In conclusion, in many ways, the topic of prophylactic antibiotics in elective foot and ankle surgery is an unusual one, in that a relative divide exists between empirical science and common practice.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
antibiotic prophylaxis
Other names: ceftriaxone
Time frame: baseline
surgical site infection are further classified as either superficial or deep. Superficial infections involve only the skin and subcutaneous tissue, whereas deep infections involve deep tissue spaces or organs
Contact information is provided by the study sponsor or research team.
Amr A Elsayed
CONTACT
Ibram R Labib
CONTACT
Assiut University
Other
Prophylactic Antibiotic in Subtalar Fusion Surgery: 24 Hours Versus 5 Days
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07720661
Arterial Occlusive Diseases, Arteriosclerosis
View Trial DetailsNCT07720154
Abdominal Hernia, Complex Ventral Hernia
Minya, Minya Governorate, Egypt
View Trial DetailsNCT07715409
Adnexal Diseases, Cesarean Section
Damietta, Damietta Governorate, Egypt
View Trial DetailsNCT07438795
Amputation, Traumatic, Barotrauma
View Trial Details