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NCT Number: NCT07508683

Pronostic Factors in Elderly Patients Admitted to the Intensive Care Unit for Aneurysmal Subarachnoid Hemorrhage

Subarachnoid hemorrhage (SAH) represents a significant proportion of hemorrhagic strokes. Severe SAH in elderly patients is associated with poorer outcomes compared to younger cohorts. Better characterization of both short- and long -term prognosis in these patients is necessary to facilitate medical decision-making in the intensive care unit (ICU)

Primary Objective:

The primary objective is to identify prognostic factors associated with poor functional outcome or death at 6 months (± 2 months) in elderly patients admitted to the ICU for SAH.

Secondary Objectives:

To evaluate in-hospital mortality among elderly patients admitted to the ICU for SAH.

To describe the causes of in-hospital death (brain death, withholding/withdrawal of life-sustaining treatment [WOLST], other medico-surgical causes) in elderly patients admitted to the ICU for SAH.

To describe the care trajectory following hospital discharge for elderly patients admitted to the ICU for SAH.

To evaluate the mean length of stay in the ICU and in the hospital (acute care) for elderly patients admitted to the ICU for SAH.

To identify prognostic factors associated with poor functional outcome or death at 1 year in elderly patients admitted to the ICU for SAH.

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Key information

Conditions

Subarachnoid Hemorrhage, Aneurysmal Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Hemorrhage Intracranial Hemorrhages Nervous System Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Subarachnoid Hemorrhage Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients hospitalized in ICU for aneurysmal subarachnoid hemorrhage
  • Aged 70 years or over the day of admission in ICU
  • Between Juin 30, 2021 and Juin 30, 2025

Exclusion criteria

  • Decline to participate

Treatment and study plan

Primary outcomes

  1. Modified Rankin Scale (MRS) et 6 months

    Time frame: 6 months after ICU discharge

    MRS : scale from 1(no symptoms) to 6 (dead) Good outcome : 0 - 2 Bad outcome: 3 - 6 The MRS grade is either collected if already available in the medical file or estimated retrospectively based on the patient neurological evaluation.

Secondary outcomes

  1. Intrahospital mortality

    Time frame: Day 28

    Intrahospital mortality = percentage of deaths occuring during the initial hospitalisation (in the ICU and the neurosurgical/neurological ward)

  2. Cause of intrahospital death

    Time frame: Day 28

    Percentage of the following categories: cerebral death, WOLST, surgical causes and medical causes

  3. Destination upon hospital discharge

    Time frame: Day 28

    Percentage of the following categories: Discharge to Home versus Rehabilitation Unit versus Another Inpatient Ward (non-neurosurgical)

  4. Modified Rankin Scale upon discharge from hospital.

    Time frame: Day 28

    MRS retrieved or estimated from patient's file data at the moment of ICU or neurosurgical ward discharge.

Study contacts

Contact information is provided by the study sponsor or research team.

Ionel M ALB, MD Intensive Care/Anesthesia

CONTACT

[email protected]

0033-661028367

Sponsors and collaborators

Lead sponsor

Central Hospital, Nancy, France

Other

Registry information

Official study title

Pronostic Factors in Elderly Patients Admitted to the Intensive Care Unit for Aneurysmal Subarachnoid Hemorrhage Multicenter Retrospective Observational Study FAPPAR-HSA

Acronym: FAPPAR-HSA

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 2, 2026
Registry last updated
Apr 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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