Prone Positioning During Delayed Cord Clamping

This study is being done to see if placing babies on the stomach or the back during delayed cord clamping after birth will improve the outcomes of preterm babies. Studies have shown that in some instances, positioning on the belly may help newborns clear their respiratory secretions. Research has shown that preterm babies can have improved breathing and require less support when placed on the stomach (prone position) rather than the back (supine position). Currently there are no guidelines for the best position for neonates to be in while receiving delayed cord clamping. The investigators are hoping to complete a research study to determine if placing preterm babies on their stomachs during the time of delayed cord clamping will improve the breathing of preterm babies and reduce the need for additional oxygen support with a breathing tube (endotracheal intubation). Depending on the outcomes of the study, the investigators are hoping to determine which position results in better outcomes for babies in both the delivery room and in the neonatal intensive care unit. If the investigators are able to determine the optimal position in this study, the investigators hope to improve the outcomes for future babies that are born preterm by placing the baby in the optimal position during delayed cord clamping.

Inclusion criteria

• Pregnant patient admitted for diagnosis that could result in a preterm delivery
• Anticipated gestational age of delivery could be between 25w+0d - 29w+6d
• Fetus without major anomalies or known genetic condition that could impact respiratory status or need for intubation at birth
• Singleton or twin gestation
• Neonate eligible for delayed cord clamping based on institutional protocol
• Patient is able to understand study procedures and is willing and able to consent

Exclusion criteria

• Triplet or higher order gestation
• Maternal or fetal/neonatal contraindication to delayed cord clamping
• Major fetal anomaly that would be expected to impact delivery room intubation rates such as:

• Major congenital cardiac defect (not isolated atrial septal defect/ventricular septal defect)
• Significant fetal arrhythmia at the time of delivery
• Fetal tumor
• Renal anhydramnios (not isolated urinary tract dilation with normal fluid)
• Congenital Diaphragmatic Hernia
• Heterotaxy
• Moderate to severe ventriculomegaly or other major brain malformation (not mild isolated ventriculomegaly)
• Airway obstruction
• Underlying genetic disease that could impact respiratory function at delivery
• Arthrogryposis (not apparently isolated clubbed foot)
• Skeletal dysplasia
• Pregnant patient is unable to understand study materials or is unwilling or unable to consent
• Acute maternal obstetric emergency that precludes time or maternal focus for the consent process to take place