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Enrolling by Invitation

NCT Number: NCT07362706

Prolonged Extubation in Gastric Cancer With OSA

This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.

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Key information

About this study

This study retrospectively included patients who underwent radical gastrectomycombined with severe obstructive sleep apnea at Qilu Hospital . Accordingto the assessment of anesthesiologists, whether the anesthetic drugs of the patients were adequatelymetabolized during the operation. The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients preoperatively diagnosed with resectable gastric cancer
  • Patients without distant organ metastasis
  • Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) >30 events/hour and SaO₂ <80%
  • Patients with cardiopulmonary function deemed suitable for surgery
  • Patients aged 18-85 years
  • Patients who voluntarily joined this study and provided written informed consent

Exclusion criteria

  • Patients with a history of or concurrent other malignant tumors
  • Patients who underwent palliative resection
  • Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled
  • Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders
  • Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study

Treatment and study plan

Prolonging the duration of postoperative endotracheal intubation before extubation.

Procedure

The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.

Primary outcomes

  1. Postoperative complications

    Time frame: 48-72 hour

    The incidence of postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.

Sponsors and collaborators

Lead sponsor

Qilu Hospital of Shandong University

Other

Registry information

Official study title

An Exploratory Study on the Impact of Prolonged Postoperative Endotracheal Extubation Time on Postoperative Complications in Gastric Cancer Patients With Severe Obstructive Sleep Apnea

Acronym: Gastric Cancer

Important dates

Study start
2023
Primary completion
2026
Study completion
2028
First posted
Jan 23, 2026
Registry last updated
Jan 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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