Shaanxi Provincial Chang'an Compulsory Isolation Drug Rehabilitation Center
Xi'an, Shaanxi, 710062, China
NCT Number: NCT06888700
This project aims to explore key brain functional and biochemical indicators associated with impaired advanced social cognition through an integrated approach encompassing unconscious control, conscious control, cognitive flexibility, problem-solving, and social interaction domains. By incorporating multimodal measures spanning physiological, neural, cognitive, psychological, and behavioral dimensions, we will develop a comprehensive intervention protocol combining course-based brain stimulation and cognitive training. The study will employ a multi-timepoint, multi-level assessment framework to track the enhancement of higher cognitive functions and brain functional recovery in individuals undergoing drug rehabilitation.
Interested in participating?
Request Info30 year–60 year
All sexes
Interventional
Not applicable
Xi'an, Shaanxi, 710062, China
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The participant cohort recruited for this study consists of individuals with substance use disorder (SUD), specifically those addicted to drugs. During the intervention phase, this group will adhere to a strict non-pharmacological intervention protocol, meaning they will not receive any form of pharmacotherapy, neurosurgical intervention, or other neuromodulation-based cognitive interventions, including but not limited to techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). This design aims to ensure the internal validity of the study results and to exclude potential confounding effects of other interventions on neuroplasticity and cognitive function.
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Used to measure problem-solving ability
Time frame: From enrollment to the end of treatment at 1 month
Used to measure collaborative problem-solving ability
Time frame: From enrollment to the end of treatment at 1 month
Used to measure interactive collaboration.
Time frame: From enrollment to the end of treatment at 1 month
Used to measure social cooperation and competition
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Used to measure problem-solving ability
Time frame: From enrollment to the end of treatment at 1 month
Used to measure collaborative problem solving ability
Time frame: From enrollment to the end of treatment at 1 month
Assessed by Wisconsin Card Quest (WCST).
Time frame: From enrollment to the end of treatment at 1 month
Assessed by stroop task
Time frame: From enrollment to the end of treatment at 1 month
Assessed by interpolation task
Shaanxi Normal University
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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