Skip to main content
OpenTrials
Completed

NCT Number: NCT02528630

Progressive Strength in Hand Osteoarthritis

Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients.

Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients.

Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Universidade Federal de Sao Paulo

São Paulo, 04023900, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • diagnostic of hand OA according to american college of rheumatology of at least 1year;
  • age over 50 years;
  • both genders;
  • pain in interphalangeal joints between 3-8 cm on a 10-cm numerical pain scale

Exclusion criteria

  • other joint disease in hands;
  • other rheumatic systemic disease;
  • surgery in hands or writs;
  • exercise or joint injection in hands in the previous 3 months;
  • disability to perform the exercises.

Treatment and study plan

Progressive resistance strength training program

Other

Patients undergo to strength training for intrinsic muscles of the hand twice a week, during 12 weeks.

Joint protection and energy conservation advice

Other

A session regarding joint protection and energy conservation for hands was done before randomization.

Primary outcomes

  1. Change in Pain

    Time frame: Baseline, after 6 and 12 weeks

    Measured by a numerical pain scale

Secondary outcomes

  1. Change in hand function

    Time frame: Baseline, after 6 and 12 weeks

    measured by AUSCAN

  2. Change in Patient satisfaction with treatment

    Time frame: 6 and 12 weeks

    Measured by a Likert scale

  3. Change in grip strength

    Time frame: Baseline, after 6 and 12 weeks

    Measured by a Grip Hydraulic Hand Dynamometer

  4. Change in hand function

    Time frame: Baseline, after 6 and 12 weeks

    Measured by COCHIN questionnaires

  5. Change in pinch stength

    Time frame: Baseline, after 6 and 12 weeks

    Measured by pinch gauge dynamometer

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Registry information

Official study title

Effectiveness of a Progressive Resistance Strength Program on Hand Osteoarthritis: a Randomized Controlled Trial

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Aug 19, 2015
Registry last updated
Feb 23, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.