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OpenTrials
Completed

NCT Number: NCT02219022

Progressive Resistance Exercise in Rheumatoid Arthritis

A randomized controlled trial with rheumatoid arthritis patients will be realized. Patients will be randomized into two groups. Experimental group will do a 12 weeks training of progressive resistance exercise for global muscles and remain with the clinical treatment and the control only remain with the clinical treatment. Patients will be evaluated at baseline, after 6, 12 and 24 weeks.

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Key information

Conditions

Rheumatoid Arthritis Arthritis Arthritis, Rheumatoid Autoimmune Diseases Connective Tissue Diseases Immune System Diseases Joint Diseases Musculoskeletal Diseases Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Rheumatic Diseases Signs and Symptoms Skin and Connective Tissue Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Universidade Federal de Sao Paulo

São Paulo, 04023-900, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Rheumatoid arthritis according to American College of Rheumatology 2010
  • Both genders
  • Age between 18 and 65 years
  • Functional class I, II and III
  • Stable medication within the three months preceding the study
  • Haven't done any kind of regular exercise (two or more times per Week) for at least three months before study start
  • Have agreed to participate in the study and signed an informed consent form.

Exclusion criteria

  • Participating in another type of study
  • Have difficulty understanding the evaluation tools with fibromyalgia
  • Joint deformities that make impossible do the exercises
  • Other musculoskeletal diseases
  • Other diseases that contraindicate exercises.

Treatment and study plan

Control Group

Other

Other names: Clinical tretament

experimental group

Other

Primary outcomes

  1. Change in pain - Visual analogue scale

    Time frame: baseline, 6, 12 and 24 weeks

Secondary outcomes

  1. Change in function capacity - Health Assessment questionaire

    Time frame: Baseline, after 6, 12 and 24 weeks

  2. Change in quality of life - Short form 36

    Time frame: baseline, after 6, 12 and 24 weeks

  3. Change in strength - 1 maximum repetition

    Time frame: baseline, after 6, 12 and 24 weeks

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Collaborators

  • Fundação de Amparo à Pesquisa do Estado de São Paulo

Registry information

Official study title

Progressive Resistance Exercise in Rheumatoid Arthritis Patients: a Randomized Controlled Trial

Important dates

Study start
2011
Primary completion
2015
Study completion
2015
First posted
Aug 18, 2014
Registry last updated
Aug 15, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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