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OpenTrials
Completed

NCT Number: NCT05503329

Prognostic Value of Lactate Levels in Patients With STEMI Undergoing Primary PCI

To assess the prognostic value of systemic arterial lactate levels in patients with ST segment elevation myocardial infarction undergoing primary PCI and correlate with the results of primary PCI and 30 days MACE follow up.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ahmed Maher teaching hospiral

Cairo, Elsayda Zainab Square, 11617, Egypt

About this study

  • Study Population: STEMI patients treated with primary PCI.
  • Study period: over 6 months.
  • Sample Size: 300 patients.

All patients received the standard care for acute STEMI patients which is the primary percutaneous intervention in addition to medications.

Hyperlactemia is defined as elevated lactic acid level in the blood. The normal blood lactate level is (0.5-1 mmol/L).

All subjects were subjected to

  • Careful history taking
  • Full cardiac examination
  • Investigations include:
  • 12 lead surface ECG.
  • Lactate level and full labs
  • Pre-discharge echocardiography
  • Peri-procedural details of primary PCI

the investigators assessed the relation between hyperlactemia and coronary flow, peak cardiac enzymes, hemodynamic parameters and MACE in 30 days follow up

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient with ST-segment elevation myocardial infarction for the first time.
  • Patients undergoing primary PCI.
  • Adult patients ≥ 18 years old.

Exclusion criteria

  • Hemodynamically unstable patients.
  • Patients with renal impairment (creatinine clearance < 30 ml/min).
  • Patients who developed flow limiting coronary dissection or mechanical complication during the procedure.
  • Patients presenting > 24 hours after symptoms onset.

Treatment and study plan

arterial lactate level

Diagnostic Test

an arterial lactate level measured from arterial sample from STEMI patients

Primary outcomes

  1. Major adverse caediac events

    Time frame: 30 days

    we follow up occurrence of death, reinfarction, repeated hospitalization and new onset heart failure

Sponsors and collaborators

Lead sponsor

Ahmed Maher Teaching Hospital

Other Gov

Registry information

Official study title

Prognostic Value of Systemic Arterial Lactate Levels in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Aug 16, 2022
Registry last updated
Aug 18, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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