Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke

This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot. Even with these treatments, about half of patients don't fully recover. The study aims to see if certain brain imaging scores, especially when combined, can better predict how well patients will recover 90 days after their stroke and if their blood vessels reopen successfully. The study will include 152 patients and last about 9 months. The goal is to find easy and reliable tools that doctors can use to make better treatment decisions.

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Key information

Conditions

Stroke, Ischemic Brain Diseases Brain Ischemia Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Ischemic Stroke Magnetic Resonance Imaging Nervous System Diseases Outcome Assessment (Health Care) Prognosis Stroke Thrombectomy Thrombolytic Therapy Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre Hospitalier de Gonesse

Gonesse, France

Location status: Recruiting

Location contact

Abdullah Blakime

CONTACT

[email protected]

0142356140

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 18 years or older
Confirmed acute ischemic stroke on imaging
Treated with both thrombolysis and thrombectomy
Clinical follow-up data available at 90 days (mRS score)

Exclusion criteria

Primary hemorrhagic stroke
Early death or loss to follow-up without evaluation
Poor-quality imaging that cannot be analyzed

Treatment and study plan

Primary outcomes

Favorable functional outcome defined as a mRS score of 0 to 2 at 90 days

Time frame: 90 days

Sponsors and collaborators

Lead sponsor

Centre Hospitalier de Gonesse

Other

Registry information

Official study title

TARGET-ASPECT (Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke)

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Jul 16, 2025
Registry last updated: Jul 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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