Skip to main content
OpenTrials
Completed

NCT Number: NCT07203924

Prognostic Importance of Physical Activity in Geriatric Patients With Acute Coronary Syndrome

This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS). A total of 207 patients aged 65 years and older were included. Physical activity level was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF) and compared with clinical outcomes and risk scores (TIMI, HEART, SVEAT). Results showed that patients with higher physical activity levels had lower rates of major adverse cardiac events (MACE) and mortality, as well as lower risk scores. The findings suggest that physical activity is an independent protective factor that improves prognosis in older patients with ACS.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Acute Coronary Syndromes Acute Coronary Syndrome Behavior Cardiovascular Diseases Geriatric Patients Heart Diseases Motor Activity Myocardial Ischemia Physical Activity Levels Vascular Diseases

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Balıkesir University Faculty of Sport Sciences / Department of Coaching Education

Balıkesir, 10145, Turkey (Türkiye)

About this study

Acute coronary syndrome (ACS) in elderly patients is associated with high morbidity and mortality, and identifying prognostic factors is clinically important. Physical activity is known to have protective cardiovascular effects, but its prognostic role in geriatric ACS patients remains unclear.

This observational study will include 207 patients aged 65 years and older who present to the emergency department with ACS. Physical activity levels will be measured using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). Activity scores will then be compared with clinical outcomes, including major adverse cardiac events (MACE), mortality, and risk stratification scores (TIMI, HEART, SVEAT).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 65 years
  • Admission to the emergency department with a diagnosis of acute coronary syndrome (ACS)
  • Ability to complete the International Physical Activity Questionnaire-Short Form (IPAQ-SF)

Exclusion criteria

  • Age < 65 years
  • Patients without ACS diagnosis
  • Patients unable to complete the IPAQ-SF questionnaire (e.g., due to severe cognitive impairment or communication problems)

Treatment and study plan

Primary outcomes

  1. Major Adverse Cardiac Events (MACE)

    Time frame: Within 30 days after emergency department admission

    Occurrence of major adverse cardiac events (MACE) including STEMI, NSTEMI, unstable angina, or cardiovascular mortality.

Secondary outcomes

  1. Physical Activity Score (IPAQ-SF)

    Time frame: At baseline (hospital admission, emergency department evaluation)

    Physical activity level measured using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Score range: 0 to 1920 MET-minutes/week. Higher scores indicate greater levels of physical activity.

  2. TIMI Risk Score

    Time frame: At baseline (emergency department evaluation)

    Thrombolysis in Myocardial Infarction (TIMI) Risk Score. Risk stratification assessed using the TIMI Risk Score, which is based on clinical history, electrocardiogram findings, troponin levels, and cardiovascular risk factors. Score range: 0 to 7. Higher scores indicate greater risk and worse prognosis.

  3. HEART Risk Score

    Time frame: At baseline (emergency department evaluation)

    HEART Risk Score (History, Electrocardiogram, Age, Risk factors, Troponin). Risk stratification assessed using the HEART Risk Score, which is based on patient history, electrocardiogram findings, age, cardiovascular risk factors, and troponin levels. Score range: 0 to 10. Higher scores indicate increased risk of major adverse cardiac events (worse prognosis).

  4. SVEAT Risk Score

    Time frame: At baseline (emergency department evaluation)

    SVEAT Risk Score (Symptoms, Vascular disease, Electrocardiogram, Age, Troponin). Risk stratification assessed using the SVEAT Risk Score, based on symptoms, history of vascular disease, electrocardiogram findings, age, and troponin levels. Score range: 0 to 10. Higher scores indicate increased cardiovascular risk and worse prognosis.

  5. All-cause Mortality

    Time frame: Within 30 days after admission

    Death from any cause among study participants after acute coronary syndrome.

Sponsors and collaborators

Lead sponsor

Balikesir University

Other

Registry information

Official study title

Prognostic Importance of Physical Activity Level in Geriatric Patients With Acute Coronary Syndrome

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Oct 2, 2025
Registry last updated
Oct 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.