Prognostic Factors Affecting Outcomes in Multivisceral en Bloc Resection for Colorectal Cancer

Determine clinical and pathological factors associated with perioperative morbidity and mortality, and oncological outcomes after multivisceral en bloc resection in patients with colorectal cancer.

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Key information

Conditions

Colorectal Neoplasms Colonic Diseases Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Between January/2009 and February/2014, 105 patients with primary colorectal cancer selected for multivisceral resection were selected from a prospective database. Clinical and pathological factors, perioperative morbidity and mortality and outcome were verified from medical records. Estimated local recurrence, and overall survival were compared using the log rank method, and Cox regression analysis was used to determine the independence of the studied parameters.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

T4 Colorectal cancer -

Exclusion criteria

Non primary Colorectal cancer -

Treatment and study plan

Multivisceral en bloc resection surgery

Procedure

Multivisceral en bloc resection for colorectal cancer in advance patients (T4)

Primary outcomes

Survival

Time frame: 3 years

diseases free survival

Secondary outcomes

Recurrence

Time frame: 3 years

months after local or systemic recurrence for colorectal cancer

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Collaborators

Antonio Rocco Imperiale
CAIO SERGIO NAHAS
Carlos Frederico Sparapan Marques
Daher Cezar Chade
Dariane Sampaio Piato
Fabio Busnardo
Guilherme Cutait Cotti
Ivan Cecconello
Rodrigo Ambar Pinto
SERGIO CARLOS NAHAS
Ulysses Ribeiro Junior
William Carlos Nahas

Registry information

Important dates

Study start: 2009
Primary completion: 2014
Study completion: 2016
First posted: Aug 8, 2016
Registry last updated: Aug 8, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed