Prognosis Predictors for Heart Failure | Clinical Trial

Key information

Conditions

Heart Failure Cardiovascular Diseases Heart Diseases Hospitalization Life Quality Morality Rehabilitation

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

This study is looking for the predictors of the survival or rehospitalization of patients with heart failure with reduced ejection fraction. Participants who are discharged from an acute heart failure hospitalization are enrolled. The prognostic factors provide information about the treatment of this disease in the future. This study is a retrospective observational study. Investigators will collect data from May 2014 to July 2019 in the heart failure center of Kaohsiung Chang Gung Memorial Hospital. A follow-up is conducted at the Kaohsiung HF center until August 2020. Investigators want to know whether the risk factors such as atrial fibrillation, diabetes, nephropathy, and some biochemical indexes can be an index that predicts future survival or rehospitalization of these patients. Besides, investigators will also explore the cardiac rehabilitation can also effectively improve the survival rate of such patients.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

inpatient, age >= 20 years old, male or female
patient with heart failure with a reduced ejection fraction and discharged alive from the hospital
received heart failure disease management program

Exclusion criteria

Estimated survival time < 6 months
Long-term bedridden for more than 3 months
Cannot tolerance exercise test due to muscular-skeletal disorder
Cannot co-operate all functional studies
Ventilator dependent
Terminal heart status
The family reject to participate in this project

Treatment and study plan

Cardiac rehabilitation

Other

multidisciplinary disease management program

Primary outcomes

all-cause mortality

Time frame: May, 2014 ~ August 2020

Number of participants that had occurrence of the mortality which is defined as all-cause mortality

Secondary outcomes

first heart failure rehospitalization

Time frame: May, 2014 ~ August 2020

Number of Participants That Had Occurrence of the Endpoint, Which is Defined as First Heart Failure (HF) Hospitalization
Change From Baseline to Month 6 and Month 12 for the Kansas City Cardiomyopathy Questionnaire 12 (KCCQ 12) Clinical Summary Score

Time frame: May , 2014 ~ August 2020

Change from baseline to Month 6 and month 12 for the Kansas City Cardiomyopathy Questionnaire short form (KCCQ12) clinical summary score. KCCQ12 is a 12-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life. KCCQ12 clinical summary score is a composite assessment of physical limitations and total symptom scores.

Scores are transformed to a range of 0-100, in which higher scores reflect better health status.

Sponsors and collaborators

Lead sponsor

Chang Gung Memorial Hospital

Other

Registry information

Official study title

Looking for Prognostic Factors That Affect the Survival of Patients With Heart Failure

Important dates

Study start: 2010
Primary completion: 2020
Study completion: 2021
First posted: Apr 9, 2021
Registry last updated: Apr 9, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed