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Completed

NCT Number: NCT04301583

Procyanidin B2 Enriched Cocoa Effects on Mitochondrial Biogenesis

The purpose of this study is to test how cocoa-rich procyanidin B2 affect the mitochondrial exercise adaptations.

Completed

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Key information

Conditions

Athletes

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad Europea de Madrid

Villaviciosa de Odón, Madrid, 28670, Spain

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men/Women
  • Age between 18 and 45 years
  • Aerobic power of oxygen consumption greater than or equal to 55 mL / kg / min

Exclusion criteria

  • Smoke
  • Any chronic disease
  • Intake of nutritional or ergogenic supplements
  • Chronic medication
  • Cocoa allergy

Treatment and study plan

procyanidin B2 enriched cocoa

Dietary Supplement

Volunteers will intake 5 grams per day of dietary supplement for 10 weeks

Primary outcomes

  1. Difference in mitochondrial number

    Time frame: 10 weeks

    Number of mitochondria in blood cells measured by qPCR using mitochondrial COX1 gene and beta globin as housekeeping nuclear gene

  2. Difference in exercise performance

    Time frame: 10 weeks

    Maximum oxygen consumption

    • of incomplete pulmonary gas exchange on VO2 max - Powers - Citado por 318
    • determination of cardiorespiratory fitness and training … - Clark - Citado por 180 Maximum oxygen consumption

Sponsors and collaborators

Lead sponsor

Universidad Europea de Madrid

Other

Registry information

Acronym: PROMETHEO

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Mar 10, 2020
Registry last updated
Nov 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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