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OpenTrials
Completed

NCT Number: NCT01222507

Processing Speed as an Objective Measure of Tinnitus

The overall purpose of this research is to assess whether both the "60 second Brain Game" and the "Brain Speed Test" computer-based programs can be used as assessment tools for objectively defining the severity of the functional impact of tinnitus.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Washington University School of Medicine

St Louis, Missouri, 63110, United States

About this study

This cross-sectional study aims to assess for deficits in brain processing speed and attention (two cognitive domains whose deficits have been implicated in tinnitus) with the use of the "Brain Speed Test".

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants must be between the ages of 18 and 80.
  • Participants must have subjective, unilateral or bilateral, non-pulsatile tinnitus of 6-months duration or longer.
  • Participants must be able to read, write and speak using the English language.
  • Participants must be able to provide informed consent.

Exclusion criteria

  • Participants with tinnitus related to Workman's Compensation Claim or other litigation-related situations.
  • Participants with active diagnoses of any acute or chronic brain-related neurological conditions that alter normal brain anatomy or function including Parkinson's disease, Multiple Sclerosis, Alzheimer's Disease, cerebral infarcts, traumatic brain injury, history of brain tumor(s), epilepsy, or dementia.
  • Participants with tinnitus related to retrocochlear lesions, cochlear implants, or other known anatomic/structural lesions of the brain, skull-base, temporal bone or ear.
  • Participants unable to hear the highest volume of the computer-based objective assessments.
  • Any medications that may affect or alter cognition including but not limited to sedatives, hypnotics, narcotics, or opiates.
  • Any medical condition the PI determines would compromise the safety of the participant or complicate the interpretation of the study results.

Treatment and study plan

Primary outcomes

  1. Brain Speed Test

    Time frame: Initial study visit

    This test involves the presentation of two consecutive high or low-frequency sound sweeps that requires the participant to correctly identify the order of presentation of the sound sweeps. Correct identification of the sound sweeps requires intact brain processing speed and attention. Scores are presented relative to age-matched controls used in validating the test. The normative data for the controls for this test will be provided by Posit Science® to the PI.

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Collaborators

  • Posit Science Corporation

Registry information

Acronym: BST

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
Oct 18, 2010
Registry last updated
Oct 25, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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