Probiotics to Improve Women's Health

The purpose of the study is explore the effect of probiotics on plasma lipopolysaccharides (LPS) concentrations, as well as insulin and glucose levels, in obese women prior to and after dietary challenges (high carbohydrate meal, high fat meal).

Completed

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Key information

Conditions

Healthy Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Arkansas Children's Nutrition Center

Little Rock, Arkansas, 72202, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

BMI=30-40 kg/m2
Healthy, age 18 or older
Not consuming yogurt or cultured milk regularly (</= 1x/wk) or any probiotic supplement

Exclusion criteria

Medical conditions or medications that may affect metabolism as determined by the PI.

Treatment and study plan

Probiotics

Dietary Supplement

Probiotics once a day for three weeks.

Primary outcomes

Plasma LPS concentrations

Time frame: five weeks

Secondary outcomes

Glucose concentrations

Time frame: five weeks

Sponsors and collaborators

Lead sponsor

Arkansas Children's Hospital Research Institute

Other

Registry information

Important dates

Study start: 2012
Primary completion: 2019
Study completion: 2019
First posted: Feb 28, 2013
Registry last updated: Dec 20, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed