Probiotic Improve Constipation

Inclusion criteria

(1) Age 18-65 years; (2) Constipated patients (less than 3 bowel movements per week and/or Bristol Scale type 1 and 2); (3) Able to complete the study according to the trial protocol; (4) Patients who have signed the informed consent form; (5) Study participants (including male study participants) have no plans to have children within 14 days prior to screening and within 6 months after the end of the trial and voluntarily use effective contraception.

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Exclusion criteria

• Those who have taken a substance with a similar function to the test subject in a short period of time, affecting their judgment of the results;
• Patients who changed their diet during the study;
• Patients with severe allergies and immunodeficiency;
• Pregnant, breastfeeding, or women planning to become pregnant;
• Those with severe diseases of vital organs such as the cardiovascular system, lungs, liver, and kidneys, diabetes, thyroid disease, severe metabolic diseases, malignant tumors, or severe immune system diseases;
• Those who have used antibiotics in the past two weeks;
• Those with severe psychological or mental illnesses;
• Those who did not consume the test sample as required or did not follow up on time, resulting in the inability to determine the efficacy;
• Other study participants deemed unsuitable by the researchers. -