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OpenTrials
Completed

NCT Number: NCT02150642

Probing Neural Circuitry for the Control of Movement

The investigators are interested in examining 1) the basic organization of spinal and cortical circuitry for the control of movement and 2) the influence of injury of these circuits. To investigate the neuronal circuitry, the investigators use various types of mechanical or electrical stimulation of the limbs, transcranial magnetic stimulation of the cortex and galvanic vestibular stimulation in both uninjured human subjects and subjects with a neurological injury (such as spinal cord injury, or Parkinsons's disease).

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Key information

Conditions

Neurological Movement Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Zurich

Zurich, 8008, Switzerland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • control subjects: no neurological movement disorder
  • patients: neurological movement disorder

Exclusion criteria

patients and control subjects:

  • presence of any central psychiatric disorder that precludes subject from giving informed and voluntary consent
  • presence of any cardiovascular conditions or limitations that restrict the ability to walk on a treadmill continuously for more than 20 minutes
  • for the electrical stimulation examination, subjects with metal implants are also excluded
  • for the TMS and GVS examination, subjects with the following conditions are excluded: metal implants in the head, cardiac pacemakers, history of migraine headaches, history of major head injury, history of stroke, history of seizures, previous brain neurosurgery, unstable medical conditions, major psychiatric disorders, pregnancy -

Treatment and study plan

Primary outcomes

  1. Spinal reflex activity

    Time frame: one day

    Spinal reflex activity will be assessed by electrical nerve stimulation

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Important dates

Study start
2004
Primary completion
2020
Study completion
2020
First posted
May 30, 2014
Registry last updated
Aug 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.